PEMERIKSAAN MIKROBIOLOGI PADA ASPERGILOSIS PULMONAL

Authors

  • Rifta Sari Program Studi Mikrobiologi Klinik, Fakultas Kedokteran, Universitas Indonesia
  • Ahmad Arfan Program Studi Mikrobiologi Klinik, Fakultas Kedokteran, Universitas Indonesia
  • Anis Karuniawati Program Studi Mikrobiologi Klinik, Fakultas Kedokteran, Universitas Indonesia
  • Budi Haryanto Program Studi Mikrobiologi Klinik, Fakultas Kedokteran, Universitas Indonesia

DOI:

https://doi.org/10.31004/prepotif.v10i1.54309

Keywords:

aspergilosis pulmonal, microbiological evaluation, lung disease

Abstract

Aspergilosis pulmonal merupakan infeksi jamur oportunistik yang disebabkan oleh Aspergillus spp. dan memiliki spektrum klinis luas, mulai dari bentuk alergi, kronik, hingga invasif yang mengancam jiwa. Peningkatan jumlah pasien imunokompromais, penyakit paru kronis, serta penggunaan kortikosteroid jangka panjang berkontribusi terhadap meningkatnya insidensi aspergilosis paru. Diagnosis penyakit ini masih menjadi tantangan karena gejala klinis dan temuan radiologis sering tidak spesifik serta menyerupai penyakit paru lain, seperti tuberkulosis dan keganasan paru. Artikel ini bertujuan untuk mengkaji secara komprehensif pemeriksaan mikrobiologi pada aspergilosis pulmonal, meliputi pemeriksaan mikroskopis langsung, kultur jamur, identifikasi spesies, uji kepekaan antijamur, pemeriksaan serologi, serta deteksi molekuler. Metode yang digunakan adalah studi kepustakaan dengan pendekatan deskriptif naratif terhadap literatur ilmiah nasional dan internasional sepuluh tahun terakhir. Hasil kajian menunjukkan bahwa pemeriksaan mikrobiologi memegang peranan penting dalam menunjang diagnosis aspergilosis pulmonal, namun harus diinterpretasikan bersama data klinis dan radiologis untuk membedakan kolonisasi, kontaminasi, dan infeksi aktif. Cairan bronchoalveolar lavage (BAL) merupakan spesimen terbaik untuk berbagai metode diagnostik. Kombinasi pemeriksaan kultur, serologi, dan biomarker jamur seperti galaktomanan dapat meningkatkan akurasi diagnosis dan membantu penatalaksanaan yang tepat.

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Published

2026-02-13

How to Cite

Sari, R., Arfan, A., Karuniawati, A., & Haryanto, B. (2026). PEMERIKSAAN MIKROBIOLOGI PADA ASPERGILOSIS PULMONAL. PREPOTIF : JURNAL KESEHATAN MASYARAKAT, 10(1), 175–185. https://doi.org/10.31004/prepotif.v10i1.54309

Issue

Vol. 10 No. 1 (2026): APRIL 2026

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Articles

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Copyright (c) 2026 Rifta Sari, Ahmad Arfan, Anis Karuniawati, Budi Haryanto

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