TRANSARTERIAL EMBOLIZATION OF BRONCHIAL ARTERY FOR HEMOPTYSIS ON END-STAGE LUNG CANCER PATIENT : A CASE SERIES
DOI:
https://doi.org/10.31004/prepotif.v9i3.52516Keywords:
adenokarsinoma, embolisasi arteri bronkial, hemoptisis, metastasis, polyvinyl alcoholAbstract
Bronchial artery embolization (BAE) merupakan teknik endovaskular invasif minimal yang memberikan manfaat diagnostik sekaligus terapeutik dalam penanganan hemoptisis yang mengancam jiwa. Pada pasien dengan keganasan paru, BAE telah ditetapkan sebagai intervensi paliatif yang efektif, terutama ketika reseksi bedah dikontraindikasikan akibat kondisi penyakit yang lanjut. Case series ini mendeskripsikan dua pasien dengan hemoptisis terkait tumor, yakni satu pasien dengan adenokarsinoma paru stadium akhir dan satu pasien lainnya dengan keterlibatan metastasis paru, yang keduanya menjalani prosedur BAE superselektif menggunakan bahan emboli yang berbeda. Presentasi klinis, temuan pencitraan, teknik prosedural, dan luaran klinis ditinjau secara mendalam untuk mengevaluasi efektivitas tindakan. Pada kasus pertama, embolisasi dilakukan menggunakan partikel polyvinyl alcohol (PVA) berukuran 500–710 µm, sedangkan pada kasus kedua digunakan mikrosfer Embosphere berukuran 300–500 µm. Hasil prosedur menunjukkan bahwa kedua pasien mencapai hemostasis lengkap dengan pengurangan vascular blush yang signifikan tanpa disertai komplikasi pasca-prosedur. Selama masa pemantauan, tidak ditemukan adanya kekambuhan hemoptisis pada kedua pasien tersebut. Temuan ini menunjukkan bahwa BAE adalah intervensi yang aman, efektif, dan dapat diulang untuk mengontrol perdarahan pada keganasan paru. Luaran ini sejalan dengan literatur sebelumnya yang mendukung BAE sebagai pilihan paliatif esensial bagi pasien dengan kanker paru stadium lanjut atau metastatik, guna meningkatkan kualitas hidup melalui kontrol perdarahan yang optimal.References
Fujita T, Tanabe M, Moritani K, Matsunaga N, Matsumoto T. (2014). Immediate and late outcomes of bronchial and systemic artery embolization for palliative treatment of patients with nonsmall- cell lung cancer having hemoptysis. Am J Hosp Palliat Care. Sep;31(6):602-7. doi: 10.1177/1049909113499442. Epub 2013 Aug 5. PMID: 23921291.
Gerontol Int. (2017). Jul;17(7):1045-1047. doi: 10.1111/ggi.13118. Epub 2017 Jul 2. PMID: 28670849.
Gershman E, Guthrie R, Swiatek K, Shojaee S. (2019). Management of hemoptysis in patients with lung cancer. Ann Transl Med. Aug;7(15):358. doi: 10.21037/atm.2019.04.91. PMID: 31516904; PMCID: PMC6712256.
Han K, Yoon KW, Kim JH, Kim GM. (2019). Bronchial Artery Embolization for Hemoptysis in Primary Lung Cancer: A Retrospective Review of 84 Patients. J Vasc Interv Radiol. Mar;30(3):428-434. doi: 10.1016/j.jvir.2018.08.022. PMID: 30819488.
Kettenbach J, Ittrich H, Gaubert JY, Gebauer B, Vos JA. (2022). CIRSE Standards of Practice on Bronchial Artery Embolisation. Cardiovasc Intervent Radiol. Jun;45(6):721-732. doi: 10.1007/s00270-022-03127-w. Epub 2022 Apr 8. PMID: 35396612; PMCID: PMC9117352.
Larici AR, Franchi P, Occhipinti M, Contegiacomo A, del Ciello A, Calandriello L, Storto ML, Marano R, Bonomo L. (2014). Diagnosis and management of hemoptysis. Diagn Interv Radiol. Jul-Aug;20(4):299-309. doi: 10.5152/dir.2014.13426. PMID: 24808437; PMCID: PMC4463269.
Liu S, Wang QD, Li Q, Yu GJ, Xu HC. (2021). CalliSpheres drug-eluting beads trans-bronchial artery chemoembolization for refractory non-small cell lung cancer. Zhong Guo Lin Chuang Yan Jiu.;1:56–60.
Lorenz JM, Navuluri R. (2019). Embolization of Chest Neoplasms: The Next Frontier in Interventional Oncology? Semin Intervent Radiol. Aug;36(3):176-182. doi: 10.1055/s-0039-1692658. Epub 2019 Aug 19. PMID: 31435125; PMCID: PMC6699877.
Myers DJ, Wallen JM. (2023). Lung Adenocarcinoma. Jun 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 30137862.
Ouchi Y, Rakugi H, Arai H, Akishita M, Ito H, Toba K, Kai I; Joint Committee of Japan Gerontological Society (JGLS) and Japan Geriatrics Society (JGS) on the definition and classification of the elderly. Redefining the elderly as aged 75 years and older: Proposal from the Joint Committee of Japan Gerontological Society and the Japan Geriatrics Society. Geriatr
Samara KD, Tsetis D, Antoniou KM, Protopapadakis C, Maltezakis G, Siafakas NM. (2011). Bronchial artery embolization for management of massive cryptogenic hemoptysis: a case series. J Med Case Rep. Feb 10;5:58. doi: 10.1186/1752-1947-5-58. PMID: 21310060; PMCID: PMC3049744.
Seki A, Shimono C. (2017). Transarterial chemoembolization for management of hemoptysis: initial experience in advanced primary lung cancer patients. Jpn J Radiol. Sep;35(9):495-504. doi: 10.1007/s11604-017-0659-2. Epub 2017 Jun 12. PMID: 28608003.
Shahkar L, Bigdeli N, Mazandarani M, Lashkarbolouk N. (2023). A Rare Case of Pulmonary Adenocarcinoma in an 8-Year-Old Patient with Persistent Respiratory Manifestation: A Case Report Study. Case Rep Oncol. Aug 28;16(1):739-745. doi: 10.1159/000531986. PMID: 37933310; PMCID: PMC10625820.
Zhou S, Zhang J, Meng X, Meng Y, Han X. (2022). Case Report: Bronchial artery embolization and chemoradiotherapy for central squamous cell lung carcinoma with rapid regression. Front Oncol. Dec 14;12:1026087. doi: 10.3389/fonc.2022.1026087. PMID: 36591505; PMCID: PMC9795177.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Koesbandono Koesbandono, Rio Hermawan, Ryan Yudistiro, Ade Nurlina

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).







