LIPOMA INTRAVENTRIKEL DENGAN KADAR TRIGLISERIDA TINGGI SEBAGAI PENYEBAB NYERI KEPALA SEKUNDER : SEBUAH LAPORAN KASUS
DOI:
https://doi.org/10.31004/prepotif.v9i3.51990Keywords:
hipertrigliseridemia, lipoma intraventrikular, nyeri kepala sekunderAbstract
Lipoma intraventrikular merupakan lesi intrakranial jinak yang jarang ditemukan dan umumnya asimtomatik, namun dapat menimbulkan gejala neurologis bila disertai faktor risiko metabolik seperti dislipidemia. Seorang laki-laki berusia 35 tahun datang dengan nyeri kepala kronis non-pulsatil dengan NRS 6 sejak tiga bulan, tidak membaik dengan terapi konservatif, serta memiliki riwayat konsumsi makanan tinggi lemak dan keluarga dengan dislipidemia. Tekanan darah 160/100 mmHg, pemeriksaan fisik umum dan status neurologi dalam batas normal, dan pemeriksaan laboratorium menunjukkan hipertrigliseridemia berat (2410 mg/dL). Berdasarkan panduan ICHD-3, pasien memenuhi kriteria chronic tension-type headache, serta terdapat sefalgia sekunder terkait hipertensi dan hipertrigliseridemia, disertai lipoma intraventrikular. Pemeriksaan MRI kepala memperlihatkan lesi berdensitas lemak konsisten dengan lipoma intraventrikular pada ventrikel lateralis kanan (8,2 × 6,2 mm) dan ventrikel ketiga (8,3 × 16,6 mm). Pasien diberikan fenofibrate 600 mg dua kali sehari dan terapi simptomatik berupa parasetamol 1000 mg dua kali sehari eperisone 50 mg dua kali sehari. Didapatkan perbaikan klinis nyeri kepala menjadi NRS 2, tekanan darah 120/80, disertai penurunan kadar trigliserida menjadi 110 mg/dL dicapai setelah terapi.References
Aikawa, Y., Sato, T., & Ichibayashi, R. (2023). Pounding score of intracranial lipomas. Clinical Case Reports, 11(9). https://doi.org/10.1002/ccr3.7948
Arshad, F., Kulanthaivelu, K., & Yadav, R. (2025). Intracranial lipoma: an incidental finding and a rare cause of secondary headache. International Journal of Neuroscience, 135(4), 388–391. https://doi.org/10.1080/00207454.2024.2302861
Bilir, O., Yavasi, O., Ersunan, G., Kayayurt, K., & Durakoglugil, T. (2014). Incidental Finding in a Headache Patient: Intracranial Lipoma. Western Journal of Emergency Medicine, 15(4), 361–362. https://doi.org/10.5811/westjem.2014.4.21298
Classification - ICHD-3. (n.d.). Retrieved October 12, 2025, from https://ichd-3.org/classification-outline/
Elgassim, M. A. M., Wafer, A., Ahmed, A., Elfaki, A., Satti, A., & Anjum, S. (2022). Intracranial Lipoma Extending Extracranially in a Five-Year-Old Patient. Cureus. https://doi.org/10.7759/cureus.21816
Gaillard, F., Knipe, H., & Campos, A. (2008). Intracranial lipoma. Radiopaedia.Org. https://doi.org/10.53347/RID-1520
Januário, G. (2023). A Clinical Case Report About an Intracranial Lipoma. International Journal of Clinical Oncology and Cancer Research. https://doi.org/10.11648/j.ijcocr.20230801.12
Kalekar, T., M, S., Reddy, L. P., Prabhu, A. S., & Lamghare, P. (2023). Neuroimaging Spectrum of Intracranial Lipomas. Cureus. https://doi.org/10.7759/cureus.35063
Palasamudram Kumaran, S., Reddy K, S., Harish, P., Ghosal, N., & Nagappa Sriramanakoppa, N. (2024). Fat in the brain: Facts and features. The Neuroradiology Journal, 37(5), 531–545. https://doi.org/10.1177/19714009221150848
Prakash, A., Wadhawan, G., Singh, R., & Thakkar, K. (2024). Study on the Correlation between Hyperlipidemia and Lipoma. International Journal of Pharmaceutical and Clinical Research, 16(2), 1525–1530.
Radiologist, M. A., & Argeta, M. (2024). Cite this article: Argeta M. Pericallosal Lipoma with Intraventricular Extension. J Clin Images, 7(1), 1153. http://meddocsonline.org/
Santos, P. E. M. S., Silva, I. R., Peres, M. F. P., & Silva-Néto, R. P. (2019). Intracranial lipoma manifesting with change in preexisting headache characteristics. Headache Medicine, 10(4), 203–204. https://doi.org/10.48208/HeadacheMed.2019.31
Wardhana, D. P. W., Lauren, C., Awyono, S., Saputra, H., & Rosyidi, R. M. (2024). Intracranial lipoma in the cerebral convexity of a 40-year-old man: a case report. International Journal of Surgery Open, 62(3), 234–238. https://doi.org/10.1097/IO9.0000000000000063
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Copyright (c) 2025 Elisya Shafa Ananda Maurika, Ismi Adhanisa, Shofiatul Mumaiyyizah, Hari Andang Sasongko, Maula Nuruddin Gaharu, Lydia Agustina, Djung Lilya Wati
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