UNMASKING TUBO-OVARIAN ABSCESS WITH ABSENCE OF CLASSIC SIGNS IN A 32-YEAR-OLD WOMAN AFTER A DECADE OF INFERTILITY - A CASE REPORT

Authors

  • Hansel Sanchia Dr. (H.C.) Ir. Soekarno Regional General Hospital, Bangka Belitung Islands, Krida Wacana
  • Yoza Firdaoz Christian University, Jakarta Dr. (H.C.) Ir. Soekarno Regional General Hospital, Bangka Belitung Islands
  • Alexander Alexander Krida Wacana Christian University Jakarta
  • RM Reza I Arnansyah Dr. (H.C.) Ir. Soekarno Regional General Hospital, Bangka Belitung Islands, University of Lampung, Lampung

DOI:

https://doi.org/10.31004/prepotif.v9i3.48518

Keywords:

Tubo-Ovarian Abscess, Pelvic Inflammatory Disease, Infertility, Antibiotics, Surgery

Abstract

Tubo-Ovarian Abscess (TOA) is an infection in the adnexal area often caused by Pelvic Inflammatory Disease (PID). This infection is usually due to polymicrobial bacteria and can occur as a result of the spread of intra-abdominal infections. Symptoms include abdominal pain, fever, and leukocytosis, with additional symptoms such as vaginal discharge and nausea. Diagnosis is made through blood tests, imaging, and cultures. The primary treatment is antibiotics, and abscess drainage via surgery is considered if antibiotic therapy is ineffective. A 32-year-old woman with a history of an endometrial cyst presented with right lower quadrant pain and dysuria. Despite previously normal CA 19-9 and CA 125 levels, an ultrasound revealed an 8.33 cm cyst. The patient had a history of dysmenorrhea and no history of sexually transmitted infections. During surgery, a tubo-ovarian abscess with pus was discovered and subsequently drained. Post-operative recovery was successful, and the patient was discharged with a prescription for oral antibiotics and scheduled for outpatient follow-up. This case report highlights the absence of clinical manifestations such as fever or leukocytosis, which initially led to a misdiagnosis. This was only recognized after surgical intervention. The case illustrates that TOA can affect fertility, with the likely cause being a history of prior In Vitro Fertilization (IVF). These findings emphasize the importance of accurate diagnosis and a collaborative approach in managing TOA to improve patient outcomes. Further research is needed to understand the long-term impacts of TOA on reproductive health.

References

Biswas, L., Tyc, K., El Yakoubi, W., Morgan, K., Xing, J., & Schindler, K. (2021). Meiosis interrupted: the genetics of female infertility via meiotic failure. Reproduction, 161(2), R13–R35. https://doi.org/10.1530/REP-20-0422

Christiansen, O. B., Nielsen, H. S., & Kolte, A. M. (2006). Inflammation and miscarriage. Seminars in Fetal and Neonatal Medicine, 11(5), 302–308. https://doi.org/10.1016/j.siny.2006.03.001

Dudek, J. E., Białaszek, W., & Gabriel, M. (2021). Quality of life, its factors, and sociodemographic characteristics of Polish women with lipedema. BMC Women’s Health, 21(1), 27. https://doi.org/10.1186/s12905-021-01174-y

Fite, E., Fitzgerald, J., & Kistenfeger, Q. (2020). Hydronephrosis Due to Bilateral Tubo-ovarian Abscess. Clinical Practice and Cases in Emergency Medicine, 4(1), 92–93. https://doi.org/10.5811/cpcem.2019.10.44568

Gkrozou, F., Tsonis, O., Daniilidis, A., Navrozoglou, I., & Paschopoulos, M. (2021). Tubo-ovarian abscess: Exploring optimal treatment options based on current evidence. Journal of Endometriosis and Pelvic Pain Disorders, 13(1), 10–19. https://doi.org/10.1177/2284026520960649

Guan, Z., Liu, J., Blazek, K., & Guan, X. (2019). Robotic Single-Site Tubal Reanastomosis: The Robotic Factor. Journal of Minimally Invasive Gynecology, 26(4), 607. https://doi.org/10.1016/j.jmig.2018.08.023

Kairys, N., & Roepke C. (2024). Tubo-Ovarian Abscess. Treasure Island (FL): StatPearls Publishing.

Kilani, R., Aleyadeh, W., Atieleh, L. A., Al Suleimat, A. M., Khadra, M., & Hawamdeh, H. M. (2018). Inter-observer variability in fetal biometric measurements. Taiwanese Journal of Obstetrics and Gynecology, 57(1), 32–39. https://doi.org/10.1016/j.tjog.2017.12.006

Menezes, M. L. B., Giraldo, P. C., Linhares, I. M., Boldrini, N. A. T., & Aragon, M. G. (2021). Brazilian Protocol for Sexually Transmitted infections, 2020: pelvic inflammatory disease. Revista Da Sociedade Brasileira de Medicina Tropical, 54(suppl 1). https://doi.org/10.1590/0037-8682-602-2020

Mitsunami, M., Mínguez-Alarcón, L., Florio, A. A., Wang, S., Attaman, J. A., Souter, I., Hauser, R., & Chavarro, J. E. (2023). Intake of soy products and soy isoflavones in relation to ovarian reserve. Fertility and Sterility, 119(6), 1017–1029. https://doi.org/10.1016/j.fertnstert.2023.02.039

Munro, K., Gharaibeh, A., Nagabushanam, S., & Martin, C. (2018). Diagnosis and management of tubo‐ovarian abscesses. The Obstetrician & Gynaecologist, 20(1), 11–19. https://doi.org/10.1111/tog.12447

Nama, V., & Kalu, E. (2009). Management of endometrioma in women embarking on IVF: paucity of good quality evidence. Fertility and Sterility, 92(6), e63. https://doi.org/10.1016/j.fertnstert.2009.09.003

NG, C. M., BLACKMAN, M. R., WANG, C., & SWERDLOFF, R. S. (2004). The Role of Carnitine in the Male Reproductive System. Annals of the New York Academy of Sciences, 1033(1), 177–188. https://doi.org/10.1196/annals.1320.017

Patil, M., Gharde, P., Reddy, K., & Nayak, K. (2024). Comparative Analysis of Laparoscopic Versus Open Procedures in Specific General Surgical Interventions. Cureus. https://doi.org/10.7759/cureus.54433

Puissant, G., Fellah, L., & Perlepe, V. (2023). Multimodality Imaging of Pelvic Inflammatory Disease Complicated with Tubo-Ovarian Abscess. Journal of the Belgian Society of Radiology, 107(1). https://doi.org/10.5334/jbsr.3061

Rowhani-Rahbar, A., & Moe, C. (2019). School Shootings in the U.S.: What Is the State of Evidence? Journal of Adolescent Health, 64(6), 683–684. https://doi.org/10.1016/j.jadohealth.2019.03.016

Tang, H., Zhou, H., & Zhang, R. (2022). Antibiotic Resistance and Mechanisms of Pathogenic Bacteria in Tubo-Ovarian Abscess. Frontiers in Cellular and Infection Microbiology, 12. https://doi.org/10.3389/fcimb.2022.958210

Tran, T. N., & Schimenti, J. C. (2019). A segregating human allele of SPO11 modeled in mice disrupts timing and amounts of meiotic recombination, causing oligospermia and a decreased ovarian reserve†. Biology of Reproduction, 101(2), 347–359. https://doi.org/10.1093/biolre/ioz089

Wang, S., Li, B., Duan, H., Chen, C., Guo, Y., & Li, T. C. (2020). Chinese Expert Consensus on the Management of Patients with Emergent Gynecologic Hemorrhage during the Coronavirus Disease Pandemic. Journal of Minimally Invasive Gynecology, 27(6), 1435–1437. https://doi.org/10.1016/j.jmig.2020.06.020

Zhao, H., & Jin, Y. (2017). Signaling networks in the control of pluripotency. Current Opinion in Genetics & Development, 46, 141–148. https://doi.org/10.1016/j.gde.2017.07.013

Zhu, S., Ballard, E., Khalil, A., Baartz, D., Amoako, A., & Tanaka, K. (2021). Impact of early surgical management on tubo-ovarian abscesses. Journal of Obstetrics and Gynaecology, 41(7), 1097–1101. https://doi.org/10.1080/01443615.2020.1821620

Zografou Themeli, M., Nirgianakis, K., Neumann, S., Imboden, S., & Mueller, M. D. (2022). Endometriosis is a risk factor for recurrent pelvic inflammatory disease after tubo-ovarian abscess surgery. Archives of Gynecology and Obstetrics, 307(1), 139–148. https://doi.org/10.1007/s00404-022-06743-6

Downloads

Published

2025-12-30

How to Cite

Sanchia, H., Firdaoz, Y., Alexander, A., & Arnansyah, R. R. I. (2025). UNMASKING TUBO-OVARIAN ABSCESS WITH ABSENCE OF CLASSIC SIGNS IN A 32-YEAR-OLD WOMAN AFTER A DECADE OF INFERTILITY - A CASE REPORT. PREPOTIF : JURNAL KESEHATAN MASYARAKAT, 9(3), 10236–10243. https://doi.org/10.31004/prepotif.v9i3.48518