KARAKTERISTIK DAN HASIL PENGOBATAN PASIEN TUBERKULOSIS SELAMA DAN PASCA-PANDEMI COVID-19 DI INDONESIA
DOI:
https://doi.org/10.31004/prepotif.v9i2.45611Keywords:
keberhasilan pengobatan, pandemi COVID-19, tuberkulosisAbstract
Pandemi Coronavirus Disease 2019 (COVID-19) memberikan dampak yang besar di Indonesia, termasuk dalam pelayanan tuberkulosis (TBC). Di Indonesia, belum banyak penelitian sebelumnya yang melakukan analisis tingkat nasional terkait gambaran keberhasilan pengobatan TBC pada masa pandemi COVID-19. Penelitian ini ditujukan untuk menganalisis gambaran karakteristik pasien dan hasil akhir pengobatan TBC sensitif obat (SO) selama dan pasca-pandemi COVID-19 di Indonesia. Penelitian epidemiologi deskriptif ini melakukan analisis terhadap seluruh pasien didiagnosis positif TBC SO di Indonesia yang memulai pengobatan TBC pada tahun 2020-2023 dan dilaporkan melalui sistem informasi TBC (SITB) milik Kementerian Kesehatan RI. Tingkat keberhasilan pengobatan dari pasien yang memulai pengobatan tahun 2020-2022 adalah sebesar 88% sementara pada tahun 2023 sebesar 87%. Tingkat keberhasilan pengobatan TBC tertinggi berasal dari kelompok usia <15 tahun, perempuan, tes cepat molekuler (TCM) tidak diperiksa atau tidak diketahui, terkonfirmasi bakteriologis, pasien TBC paru, menerima OAT program dan dilakukan pemeriksaan pemantauan akhir pengobatan serta mendapatkan pengobatan di puskesmas dan klinik pemerintah, baik selama maupun pasca-pandemi COVID-19. Penelitian ini mengindikasikan bahwa tidak terdapat banyak perbedaan gambaran karakteristik pasien dan belum terlihat peningkatan keberhasilan pengobatan TBC antara periode selama dan setelah pandemi COVID-19. Berbagai tantangan dalam pelayanan dan pencapaian keberhasilan pengobatan TBC yang teridentifikasi perlu dilakukan analisis lebih lanjut dan diintegrasikan dalam rencana mitigasi selanjutnya.References
Barteka, G., Bwayo, D., Matovu, J. K. B., Wanume, B., Alunyo, J. P., Sseguya, R., Masaba, J. P., & Obbo, J. S. (2025). Treatment outcomes and predictors of success for multidrug resistant tuberculosis MDR TB in Ugandan regional referral hospitals. Scientific Reports, 15(1), 14144. https://doi.org/10.1038/s41598-025-97027-x
Djochie, R. D. A., Anto, B. P., Opare-Addo, M. N. A., & Boakye-Yiadom, J. (2025). Factors influencing treatment success in drug-susceptible tuberculosis patients in Ghana: A prospective cohort study. PLOS Global Public Health, 5(2), e0004146. https://doi.org/10.1371/journal.pgph.0004146
Gandhi, A. P., Kathirvel, S., & Rehman, T. (2022). Effect of COVID-19 lockdown on the pathway of care and treatment outcome among patients with tuberculosis in a rural part of northern India: A community-based study. Journal of Rural Medicine : JRM, 17(2), 59–66. https://doi.org/10.2185/jrm.2021-039
Garg, K., Bahurupi, Y., Aggarwal, P., & Badola, M. (2023). Impact of COVID-19 on the National Tuberculosis Elimination Program in Uttarakhand, India: A Mixed-Methods Research Study. Infection Prevention in Practice, 5(1), 100269. https://doi.org/10.1016/j.infpip.2023.100269
Jennings, K., Lembani, M., Hesseling, A. C., Mbula, N., Mohr-Holland, E., Mudaly, V., Smith, M., Osman, M., & Meehan, S.-A. (2024). A decline in tuberculosis diagnosis, treatment initiation and success during the COVID-19 pandemic, using routine health data in Cape Town, South Africa. PLOS ONE, 19(9), e0310383. https://doi.org/10.1371/journal.pone.0310383
Kemenkes. (2016). Peraturan Menteri Kesehatan RI Nomor 67 Tahun 2016 Tentang Penanggulangan Tuberkulosis.
Kemenkes. (2020a). Pedoman Nasional Pelayanan Kedokteran Tata Laksana Tuberkulosis. https://repository.Kemkes.Go.Id/Book/124
Kemenkes. (2020b). Protokol Tata Laksana Pasien Tb Dalam Masa Pandemi Covid 19. Protokol Tata Laksana Pasien Tb Dalam Masa Pandemi Covid 19. Https://Htbs.Tbindonesia.Or.Id/Wp-Content/Uploads/2020/03/Protokol-TB-dalam-Pandemi-Covid-19-2020.pdf
Kemenkes. (2021). Surat Edaran Direktur Jenderal Pencegahan Dan Pengendalian Penyakit Nomor HK.02.02/III.1/936/2021 Tentang Perubahan Alur Diagnosis Dan Pengobatan Tuberkulosis Di Indonesia. https://www.tbindonesia.or.id/wp-content/uploads/2023/12/2021_SE-Dirjen-HK.02.02_III.1_936_2021-Rev-Alur-Diagnosis-dan-Pengobatan-TB_April-2020_Final.pdf
Kemenkes. (2023). Petunjuk Teknis Pemeriksaan Tuberkulosis Menggunakan Tes Cepat Molekuler GeneXpert. https://www.tbindonesia.or.id/wp-content/uploads/2024/02/Buku-Petunjuk-Teknis-Pemeriksaan-TBC-Menggunakan-Alat-TCM-GeneXpert_2023-1.pdf
Kemenkes. (2024). Laporan Program Penanggulangan Tuberkulosis Tahun 2023. https://www.tbindonesia.or.id/wp-content/uploads/2024/12/Laporan-Program-Penanggulangan-TBC-2023_Final.pdf
Kemenkes. (2025). Dashboard Situasi COVID-19. https://infeksiemerging.kemkes.go.id/dashboard/covid-19
Sassi, A., Lestari, B. W., El Muna, K. U. N., Oga-Omenka, C., Afifah, N., Widarna, R., Huria, L., Aguilera Vasquez, N., Benedetti, A., Hadisoemarto, P. F., Daniels, B., Das, J., Pai, M., & Alisjahbana, B. (2024). Impact of the COVID-19 pandemic on quality of tuberculosis care in private facilities in Bandung, Indonesia: A repeated cross-sectional standardized patients study. BMC Public Health, 24(1), 102. https://doi.org/10.1186/s12889-023-17001-y
Sugiyono, R. I., Naysilla, A. M., Susanto, N. H., Handayani, D., Burhan, E., Karuniawati, A., Kusmiati, T., Wibisono, B. H., Riyanto, B. S., Sajinadiyasa, I. G. K., Djaharuddin, I., Sinaga, B. Y. M., Dewantara, R. D., Karyana, M., Kosasih, H., Liang, C. J., Ridzon, R., Neal, A. T., & Chen, R. Y. (2025). Treatment outcomes of pulmonary TB in adults in Indonesia. IJTLD OPEN, 2(3), 145–152. https://doi.org/10.5588/ijtldopen.24.0482
Vasquez, N. A., Oga-Omenka, C., Yellappa, V., Lestari, B. W., Sassi, A., Sheokand, S., Olusola-Faleye, B., Huria, L., Brubacher, L. J., Baruwa, E., Alisjahbana, B., & Pai, M. (2025). COVID-19 policies and tuberculosis services in private health sectors of India, Indonesia, and Nigeria. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 38, 100503. https://doi.org/10.1016/j.jctube.2024.100503
WHO. (2021). Global Tuberculosis Report 2021 (1st ed). World Health Organization.
WHO. (2022a). Global Tuberculosis Report 2022. https://www.who.int/teams/global-programme-on-tuberculosis-and-lung-health/tb-reports/global-tuberculosis-report-2022
WHO. (2022b). WHO Consolidated Guidelines on Tuberculosis. Module 5: Management of Tuberculosis in Children and Adolescents (1st ed). World Health Organization.
WHO. (2024). [TB profile]. https://worldhealthorg.shinyapps.io/tb_profiles/?_inputs_&tab=%22tables%22&lan=%22EN%22&iso2=%22ID%22&entity_type=%22country%22
Zhou, J., Li, J., Hu, Y., & Li, S. (2025). Examining the efficacy of treatment outcomes for patients with pulmonary tuberculosis in Western China: A retrospective study in a region of high incidence. BMC Public Health, 25(1), 1360. https://doi.org/10.1186/s12889-025-22543-4
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 R. A. Della Patrisia Pramesti, Trisari Anggondowati
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
