ANESTESI KETAMIN PADA TERAPI MANIPULASI ZERO POSITION PADA PASIEN FROZEN SHOULDER
DOI:
https://doi.org/10.31004/prepotif.v9i1.40577Keywords:
frozen shoulder, ketamin, zero positionAbstract
Ketamin telah memainkan peran serbaguna dalam pengobatan karena spektrum penggunaannya yang luas dalam sejarah termasuk penggunaan dalam sedasi, katalepsi, analgesia somatik, dan bronkodilatasi. Pendekatan multimodal analgesik non-opioid atau Opioid Free Anastesia(OFA) ditujukan untuk mengoptimalkan opsi tambahan intraoperatif, Beberapa meta-analisis juga telah melaporkan efek menguntungkan dari anestesi ketamin pada proses sedasi pasien yang menjalani operasi. Namun, Pemberian ketamin dosis subanestesi 0,1-0,5 mg/kg IV merupakan salah satu obat yang dapat menggantikan opioid sebagai analgetik dengan memberikan efek samping minimal. Kami menyajikan kasus seorang laki-laki berusia 49 tahun dengan diagnose medis frozen shoulder, datang dengan keluhan nyeri berat pada bahu kiri yang menyebabkan terganggunya aktifitas sehari-hari. Pasien mendapatkan tindakan manipulasi zero position untuk membantu dalam mengurangi perlengketan pada kapsul sendi bahu dengan anastesi umum menggunakan ketamin dosis rendah 0,3 mg/kgBB IV. Zero position dengan menggunakan induksi ketamin 0,3 mg/kgBB dilakukan dalam waktu 2 menit, tindakan berjalan dengan baik tanpa penyulit dan komplikasi. Kami menyajikan kasus ini untuk menunjukkan bagaimana efektivitas penggunaan ketamin pada pasien frozen shoulder yang diinduksi dengan anestesi umum dapat menyebabkan pengendalian nyeri, efek relaksasi dan fleksibilitas otot, serta peningkatan kualitas hidup pasien.References
Abdallah, C. G., Adams, T. G., Kelmendi, B., Esterlis, I., Sanacora, G., & Krystal, J. H. (2016). Ketamine's mechanism of action: a path to rapid‐acting antidepressants. Depression and anxiety, 33(8), 689-697.
Amr, Y. M. (2010). Multi-day low dose ketamine infusion as adjuvant to oral gabapentin in spinal cord injury related chronic pain: a prospective, randomized, double blind trial. Pain Physician, 13(3), 245.
Bell, R. F., & Kalso, E. A. (2018). Ketamine for pain management. Pain reports, 3(5), e674.
Beloeil, H. (2019). Opioid-Free Anaesthesia: The Need For Evidence-Based Proofs. Https://Doi.Org/10.1016/J.Accpm.2019.05.002ï
BinKharfi, M., & AlSagre, A. (2019). BET 2: Safety and efficacy of low-dose ketamine versus opioids for acute pain management in the ED. Emergency Medicine Journal, 36(2), 128-129.
Bylund, W., Delahanty, L., & Cooper, M. (2017). The case of ketamine allergy. Clinical Practice and Cases in Emergency Medicine, 1(4), 323.
Charan, S. D., Khilji, M. Y., Jain, R., Devra, V., & Saxena, M. (2018). Inhalation of ketamine in different doses to decrease the severity of postoperative sore throat in surgeries under general anesthesia patients. Anesthesia Essays and Researches, 12(3), 625-629.
Chia, P. A., Cannesson, M., & Bui, C. C. M. (2020). Opioid free anesthesia: feasible?. Current Opinion in Anesthesiology, 33(4), 512-517.
Cho, C. H., Song, K. S., Kim, B. S., Kim, D. H., & Lho, Y. M. (2018). Biological aspect of pathophysiology for frozen shoulder. BioMed Research International, 2018(1), 7274517.
Efek Ketamin pada Hiperalgesia yang Diinduksi Opioid Tersedia daring: https://clinicaltrials.gov/ct2/show/NCT00833755
Ferraro, M. C., Cashin, A. G., O'Connell, N. E., Visser, E. J., Shaheed, C. A., Wewege, M. A., ... & McAuley, J. H. (2023). Ketamine and other NMDA receptor antagonists for chronic pain. The Cochrane Database of Systematic Reviews, 2023(2).
Hubbard, M. J., Hildebrand, B. A., Battafarano, M. M., & Battafarano, D. F. (2018). Common soft tissue musculoskeletal pain disorders. Primary Care: Clinics in Office Practice, 45(2), 289-303.
Kingston, K., Curry, E. J., Galvin, J. W., & Li, X. (2018). Shoulder adhesive capsulitis: epidemiology and predictors of surgery. Journal of shoulder and elbow surgery, 27(8), 1437-1443.
Le, T. T., Cordero, I. P., Jawad, M. Y., Swainson, J., Di Vincenzo, J. D., Jaberi, S., ... & McIntyre, R. S. (2022). The abuse liability of ketamine: a scoping review of preclinical and clinical studies. Journal of psychiatric research, 151, 476-496.
Mion, G., & Villevieille, T. (2013). Ketamine pharmacology: an update (pharmacodynamics and molecular aspects, recent findings). CNS neuroscience & therapeutics, 19(6), 370-380.
Murakami, A. M., Kompel, A. J., Engebretsen, L., Li, X., Forster, B. B., Crema, M. D., ... & Guermazi, A. (2018). The epidemiology of MRI detected shoulder injuries in athletes participating in the Rio de Janeiro 2016 Summer Olympics. BMC musculoskeletal disorders, 19, 1-7.
Nichols, K. A., & Paciullo, C. A. (2019). Subdissociative ketamine use in the emergency department. Advanced Emergency Nursing Journal, 41(1), 15-22.
Park, S. Y., Kim, S. H., Noh, J. I., Lee, S. M., Kim, M. G., Kim, S. H., ... & Im Kim, S. (2010). The effect of intravenous low dose ketamine for reducing postoperative sore throat. Korean Journal of Anesthesiology, 59(1), 22-26.
Pratama, A., Pradian, E., & Erlangga, M. E. (2020). Perbandingan Efek Fentanil dengan Ketamin terhadap Skor Pemulihan Pascaanestesi Umum Diukur dengan QoR-40 serta Perubahan Tekanan Darah dan Nadi pada Operasi Odontektomi. Jurnal Anestesi Perioperatif, 8(3), 149-157.
Rianti, R., Dwimartyono, F., & Abadi, M. N. (2024). Case Report: Efek Penggunaan Low Dose Ketamin 0, 5 Mg IV Terhadap Terhadap Kejadian Post And Ponv Paska Insersi Lma. Jurnal Kesehatan Tambusai, 5(3), 6078-6088.
Robson, M. J., Elliott, M., Seminerio, M. J., & Matsumoto, R. R. (2012). Evaluation of sigma (σ) receptors in the antidepressant-like effects of ketamine in vitro and in vivo. European Neuropsychopharmacology, 22(4), 308-317.
Sin, B., Ternas, T., & Motov, S. M. (2015). The use of subdissociative‐dose ketamine for acute pain in the emergency department. Academic Emergency Medicine, 22(3), 251-257.
Swainson, J., Thomas, R. K., Archer, S., Chrenek, C., MacKay, M. A., Baker, G., ... & Demas, M. L. (2019). Esketamine for treatment resistant depression. Expert review of neurotherapeutics, 19(10), 899-911.
Valadkhani, S., Radmard, F., Saeedi, M., & Farnia, M. R. (2016). Acute angioedema in a patient who received ketamine and succinylcholine: A case report. Chinese Medical Journal, 129(18), 2264-2264.
Varì, M. R., Ricci, G., Cavallo, M., Pichini, S., Sirignano, A., & Graziano, S. (2022). Ketamine: from prescription anaesthetic to a new psychoactive substance. Current Pharmaceutical Design, 28(15), 1213-1220.
Warner, L. L., & Smischney, N. (2018). Special K with no license to kill: accidental ketamine overdose on induction of general anesthesia. The American Journal of Case Reports, 19, 10.
Wiryana, M., Sinardja, I. K., Budiart, I. G., Senapathi, T. G. A., Widnyana, M., Aryabiantara, I. W., Agung Gede Utara Hartawan, I. G., Parami, P., Novita Pradnyani, N. P., & Pradhana, A. P. (2017). Low Dose Ketamin. Bali Journal Of Anesthesiology, 1(1), 13–19. Https://Doi.Org/10.15562/Bjoa.V1i1.4
Wu, F., Kachooei, A. R., Ebrahimzadeh, M. H., Bagheri, F., Hakimi, E., Shojaie, B., & Nazarian, A. (2018). Bilateral Arm-Abduction Shoulder Radiography to Determine the Involvement of the Scapulothoracic Motion in Frozen Shoulder. Archives of Bone and Joint Surgery, 6(3), 225.
Xiao, R. C., DeAngelis, J. P., Smith, C. C., & Ramappa, A. J. (2017). Evaluating Nonoperative Treatments for Adhesive Capsulitis. Journal of Surgical Orthopaedic Advances, 26(4), 193-199.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Reghita Avrilya, Faisal Sommeng, Nuraini Abidin

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).