LITERATURE REVIEW : PENGARUH INTERMITTENT FASTING TERHADAP PENURUNAN KADAR HBA1C PENDERITA DIABETES DI ASIA
DOI:
https://doi.org/10.31004/prepotif.v8i3.39598Keywords:
Asia, Diabetes Mellitus, Intermittent FastingAbstract
Diabetes merupakan penyakit kronis yang dapat menyebabkan komplikasi serius dan meningkatkan risiko kematian. Menurut International Diabetes Federation, 60% populasi diabetes global tinggal di wilayah Asia. Salah satu indikator penting dalam pengelolaan diabetes adalah kadar hemoglobin A1c (HbA1c), yang menggambarkan pengendalian glukosa darah. Intermittent fasting (IF) telah dipertimbangkan sebagai metode non-farmakologis untuk mengontrol kadar glukosa darah, namun efeknya pada penderita diabetes di wilayah Asia masih belum banyak dibahas. Penelitian ini bertujuan untuk mengetahui pengaruh intermittent fasting terhadap penurunan kadar HbA1c pada penderita diabetes tipe 2 di wilayah Asia. Metode penelitian ini menggunakan pendekatan literature review dengan memilih artikel yang dipublikasikan antara tahun 2018 hingga 2024. Penelusuran literatur dilakukan menggunakan database MEDLINE, CENTRAL, dan ProQuest, serta dengan hand search pada referensi artikel terkait. Kriteria inklusi melibatkan studi dengan populasi penderita diabetes tipe 2 di Asia yang menerapkan intermittent fasting. Artikel yang tidak memenuhi kriteria, seperti penelitian dengan subjek hewan, dikeluarkan dari analisis. Didapatkan 23 artikel dari tiga database yang ditelusuri. Setelah diseleksi berdasarkan kriteria inklusi dan eklusi diperolah lima artikel ditambah dua artikel dari hand search. Tujuh artikel disertakan dalam analisis utama. Semua studi menunjukkan penurunan yang signifikan pada kadar HbA1c dan glukosa puasa pada penderita diabetes yang menjalani intervensi intermittent fasting. Intermittent fasting dapat menjadi alternatif pengobatan nonfarmakologis untuk menurunkan kadar HbA1c pada penderita diabetes tipe 2 di Asia. Penelitian lebih lanjut diperlukan untuk melihat dampak jangka panjang dan kaitannya dengan penggunaan insulin pada pasien dengan durasi penyakit yang lebih lama.References
Albosta, M., & Bakke, J. (2021). Intermittent fasting: Is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians. Clinical Diabetes and Endocrinology, 7(1), 3. https://doi.org/10.1186/s40842-020-00116-1
American Diabetes Association Professional Practice Committee. (2022). 8. Obesity and Weight Management for the Prevention and Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2022. Diabetes Care, 45(Supplement_1), S113–S124. https://doi.org/10.2337/dc22-S008
American Diabetes Association Professional Practice Committee, ElSayed, N. A., Aleppo, G., Bannuru, R. R., Bruemmer, D., Collins, B. S., Ekhlaspour, L., Gaglia, J. L., Hilliard, M. E., Johnson, E. L., Khunti, K., Lingvay, I., Matfin, G., McCoy, R. G., Perry, M. L., Pilla, S. J., Polsky, S., Prahalad, P., Pratley, R. E., … Gabbay, R. A. (2024). 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2024. Diabetes Care, 47(Supplement_1), S20–S42. https://doi.org/10.2337/dc24-S002
Andriessen, C., Fealy, C. E., Veelen, A., Van Beek, S. M. M., Roumans, K. H. M., Connell, N. J., Mevenkamp, J., Moonen-Kornips, E., Havekes, B., Schrauwen-Hinderling, V. B., Hoeks, J., & Schrauwen, P. (2022). Three weeks of time-restricted eating improves glucose homeostasis in adults with type 2 diabetes but does not improve insulin sensitivity: A randomised crossover trial. Diabetologia, 65(10), 1710–1720. https://doi.org/10.1007/s00125-022-05752-z
Carter, S., Clifton, P. M., & Keogh, J. B. (2018). Effect of Intermittent Compared With Continuous Energy Restricted Diet on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Noninferiority Trial. JAMA Network Open, 1(3), e180756. https://doi.org/10.1001/jamanetworkopen.2018.0756
Che, T., Yan, C., Tian, D., Zhang, X., Liu, X., & Wu, Z. (2021). Time-restricted feeding improves blood glucose and insulin sensitivity in overweight patients with type 2 diabetes: A randomised controlled trial. Nutrition & Metabolism, 18(1), 88. https://doi.org/10.1186/s12986-021-00613-9
Deshmane, A. R., & Muley, A. (2024). Quality of Life and Its Association With Time in Range Among People With Type 2 Diabetes Mellitus Following Different Dietary Interventions: A Crossover Clinical Trial. Cureus. https://doi.org/10.7759/cureus.57624
Grajower, M. M., & Horne, B. D. (2019). Clinical Management of Intermittent Fasting in Patients with Diabetes Mellitus. Nutrients, 11(4), 873. https://doi.org/10.3390/nu11040873
Guo, L., Xi, Y., Jin, W., Yuan, H., Qin, G., Chen, S., Zhang, L., Liu, Y., Cheng, X., Liu, W., & Yu, D. (2024). A 5:2 Intermittent Fasting Meal Replacement Diet and Glycemic Control for Adults With Diabetes: The EARLY Randomized Clinical Trial. JAMA Network Open, 7(6), e2416786. https://doi.org/10.1001/jamanetworkopen.2024.16786
Khalafi, M., Habibi Maleki, A., Symonds, M. E., Rosenkranz, S. K., Rohani, H., & Ehsanifar, M. (2024). The effects of intermittent fasting on body composition and cardiometabolic health in adults with prediabetes or type 2 diabetes: A systematic review and meta?analysis. Diabetes, Obesity and Metabolism, 26(9), 3830–3841. https://doi.org/10.1111/dom.15730
Kunduraci, Y. E., & Ozbek, H. (2020). Does the Energy Restriction Intermittent Fasting Diet Alleviate Metabolic Syndrome Biomarkers? A Randomized Controlled Trial. Nutrients, 12(10), 3213. https://doi.org/10.3390/nu12103213
Luo, W., Zhou, J., Yang, X., Wu, R., Liu, H., Shao, H., Huang, B., Kang, X., Yang, L., & Liu, D. (2022). A Chinese medical nutrition therapy diet accompanied by intermittent energy restriction alleviates type 2 diabetes by enhancing pancreatic islet function and regulating gut microbiota composition. Food Research International, 161, 111744. https://doi.org/10.1016/j.foodres.2022.111744
Magliano, D., & Boyko, E. J. (with International Diabetes Federation). (2021). IDF diabetes atlas (10th edition). International Diabetes Federation.
Msane, S., Khathi, A., & Sosibo, A. (2024). Therapeutic Potential of Various Intermittent Fasting Regimens in Alleviating Type 2 Diabetes Mellitus and Prediabetes: A Narrative Review. Nutrients, 16(16), 2692. https://doi.org/10.3390/nu16162692
Obermayer, A., Tripolt, N. J., Pferschy, P. N., Kojzar, H., Aziz, F., Müller, A., Schauer, M., Oulhaj, A., Aberer, F., Sourij, C., Habisch, H., Madl, T., Pieber, T., Obermayer-Pietsch, B., Stadlbauer, V., & Sourij, H. (2023). Efficacy and Safety of Intermittent Fasting in People With Insulin-Treated Type 2 Diabetes (INTERFAST-2)—A Randomized Controlled Trial. Diabetes Care, 46(2), 463–468. https://doi.org/10.2337/dc22-1622
Ojo, T. K., Joshua, O. O., Ogedegbe, O. J., Oluwole, O., Ademidun, A., & Jesuyajolu, D. (2022). Role of Intermittent Fasting in the Management of Prediabetes and Type 2 Diabetes Mellitus. Cureus. https://doi.org/10.7759/cureus.28800
Riddle, M. C., Cefalu, W. T., Evans, P. H., Gerstein, H. C., Nauck, M. A., Oh, W. K., Rothberg, A. E., Le Roux, C. W., Rubino, F., Schauer, P., Taylor, R., & Twenefour, D. (2021). Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes. Diabetes Care, 44(10), 2438–2444. https://doi.org/10.2337/dci21-0034
Sukkriang, N., & Buranapin, S. (2024). Effect of intermittent fasting 16:8 and 14:10 compared with control?group on weight reduction and metabolic outcomes in obesity with type 2 diabetes patients: A randomized controlled trial. Journal of Diabetes Investigation, 15(9), 1297–1305. https://doi.org/10.1111/jdi.14186
World Health Organization. (2024). Diabetes. https://www.who.int/news-room/fact-sheets/detail/diabetes
Xiaoyu, W., Yuxin, X., & Li, L. (2024). The effects of different intermittent fasting regimens in people with type 2 diabetes: A network meta-analysis. Frontiers in Nutrition, 11, 1325894. https://doi.org/10.3389/fnut.2024.1325894
Yang, X., Zhou, J., Shao, H., Huang, B., Kang, X., Wu, R., Bian, F., Hu, M., & Liu, D. (2023). Effect of an Intermittent Calorie-restricted Diet on Type 2 Diabetes Remission: A Randomized Controlled Trial. The Journal of Clinical Endocrinology & Metabolism, 108(6), 1415–1424. https://doi.org/10.1210/clinem/dgac661
Zang, B.-Y., He, L.-X., & Xue, L. (2022). Intermittent Fasting: Potential Bridge of Obesity and Diabetes to Health? Nutrients, 14(5), 981. https://doi.org/10.3390/nu14050981
Zeng, X., Ji, Q., Jiang, Z., & Xu, Y. (2024). The effect of different dietary restriction on weight management and metabolic parameters in people with type 2 diabetes mellitus: A network meta-analysis of randomized controlled trials. Diabetology & Metabolic Syndrome, 16(1), 254. https://doi.org/10.1186/s13098-024-01492-9
Zhu, S., Surampudi, P., Rosharavan, B., & Chondronikola, M. (2020). Intermittent fasting as a nutrition approach against obesity and metabolic disease. Current Opinion in Clinical Nutrition & Metabolic Care, 23(6), 387–394. https://doi.org/10.1097/MCO.0000000000000694
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