DEMAM TIFOID DENGAN INFEKSI SARS CoV-2 DI ERA ENDEMI : SEBUAH LAPORAN KASUS
DOI:
https://doi.org/10.31004/prepotif.v8i3.37276Keywords:
Antibiotik, Antivirus, Demam Tifoid, Endemi, SARS-CoV-2Abstract
Demam tifoid merupakan penyakit infeksi bakteri Salmonella enterica khususnya turunannya, yaitu typhi, paratyphi A, B dan C. Secara klasik, demam tifoid dikaitkan dengan demam berkepanjangan dengan pola step ladder, gejala gastrointestinal (seperti mual, muntah, diare, atau konstipasi), sakit kepala, kelelahan, tidak enak badan, kehilangan nafsu makan, dan batuk. SARS CoV-2 saat ini menyebabkan pandemi penyakit yang parah di seluruh dunia, menyebabkan pandemi global. Indonesia saat ini sudah menetapkan SARS CoV-2 sebagai penyakit endemi. Mayoritas orang yang terinfeksi SARS CoV-2 adalah tidak menunjukkan gejala atau mengeluhkan gejala mirip pneumonia yang terdiri dari demam, batuk, sesak napas, dan gejala virus seperti mialgia, kelelahan, dan sakit kepala. Persamaan gejala keduanya menjadi tantangan dokter dalam mendiagnosis. Seorang pria 38 tahun dengan keluhan demam, gangguan gastrointestinal dan mialgia, batuk dengan diagnosis demam tifoid dan SARS-CoV-2. Pasien diberikan terapi antibiotik dan antivirus. Demam, gangguan gastrointestinal, dan batuk merupakan gejala pada demam tifoid yang mana perlu adanya diagnosis banding lain dimasa endemi SARS-CoV-2 sehingga dapat melakukan penatalaksanaan yang tepat. Kesimpulan pada penelitian ini yaitu dokter perlu menegakkan diagnosis banding yang lebih lengkap pada pasien dengan gejala demam pada era endemi SARS-CoV-2.References
Abdul Aziz JM, Abdullah SK, Al-Ahdal TMA, Gubari MIM, Rashid MJ, Tahir KS,et al. Diagnostic bias during the COVID-19. A rare case report of Salmonella Typhi. Ann Med Surg. (2022) 74:103282. doi: 10.1016/j.amsu.2022.103282
Ahmad S, Tsagkaris C, Aborode AT, Ul Haque MT, Khan SI, Khawaja UA, Carla Dos Santos Costa A, Essar MY, Lucero-Prisno DE 3rd. A skeleton in the closet: The implications of COVID-19 on XDR strain of typhoid in Pakistan. Public Health Pract (Oxf). 2021 Nov;2:100084. doi: 10.1016/j.puhip.2021.100084. Epub 2021 Jan 23. PMID: 33521736; PMCID: PMC7826057.
Ahn, J. H. et al. Nasal ciliated cells are primary targets for SARS- CoV-2 replication in the early stage of COVID-19. J. Clin. Invest. 131, e148517 (2021).
Arora P, Thorlund K, Brenner DR, Andrews JR. Comparative accuracy of typhoid diagnostic tools: A Bayesian latent-class network analysis. PLoS Negl Trop Dis. 2019 May 8;13(5):e0007303. doi: 10.1371/journal.pntd.0007303. PMID: 31067228; PMCID: PMC6527309.
Ayoubzadeh SI, Isabel S, Coomes EA, Morris SK. Enteric fever and COVID-19 co-infection in a teenager returning from Pakistan. J Travel Med. 2021 Apr 14;28(3):taab019. doi: 10.1093/jtm/taab019. PMID: 33550371; PMCID: PMC7928753.
Badan Litbangkes Departemen Kesehatan RI. Laporan Riset Kesehatan Dasar Nasional 2007. Jakarta: Departemen Kesehatan, 2008 (online) http://www.k4health.org/system/files/laporanNasional%20Riskesdas %202007.pdf
Bhutta ZA. Current concepts in the diagnosis and treatment of typhoid fever. BMJ 2006;333:78-82.
Bogdan I, Citu C, Bratosin F, Malita D, Romosan I, Gurban CV, et al. The impact of multiplex PCR in diagnosing and managing bacterial infections in COVID-19 patients self-medicated with antibiotics. Antibiotics. (2022) 11:437. doi: 10.3390/antibiotics11040437
Burhan E, Dwi Susanto A, Isbaniah F, Aman Nasution S, Ginanjar E, Wicaksono Pitoyo C, et al. PEDOMAN TATALAKSANA COVID-19 Edisi 4 TIM EDITOR Perhimpunan Dokter Paru Indonesia (PDPI) Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia (PAPDI) Perhimpunan Dokter Anestesiologi dan Terapi Intensif Indonesia (PERDATIN) Ikatan Dokter Anak Indonesia (IDAI).
Chen C, Zhang Y, Huang J, et al. Favipiravir versus arbidol for COVID-19: A randomized clinical. MedRxiv. 2020; 10: 1-30. https://doi.org/10.1101/2020. 03.17.20037432
Cucinotta D, Vanelli M. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020 Mar 19;91(1):157-160
Hafiz Muhammad, A.G. Icksan, A.D. Harlivasari, R. Aulia, F. Susanti, L. Eldinia, Clinical, radiological features and outcome of COVID-19 patients in a secondary hospital in Jakarta, Indonesia, J. Infect. Develop. Countries 14 (7) (2020) 750–757.
Harris JB, Brooks WA. Typhoid and paratyphoid (enteric) fever. In: Magill AJ, Ryan ET, Hill DR, Solomon T, eds. Hunter’s tropical medicine and emerging infectious diseases, 9th edn. Philadelphia, PA: Elsevier, 2013: 568–76.
Hayat AS., 2011. “Evaluation of Typhidot (IgM) in early and rapid diagnosis of typhoid fever.” Professional Med. 18(2): 259-264.
Institute for Health Metrics and Evaluation. Typhoid fever–level 4 cause. Seattle, WA: Institute for Health Metrics and Evaluation, Global Burden of Disease Collaborative Network; 2020. https://www.healthdata.org/ results/gbd_summaries/2019/typhoid-fever-level-4-cause
Ivashchenko AA, Dmitriev KA, Vostokova NV, Azarova VN, Blinow AA, Egorova AN, Gordeev IG, Ilin AP, Karapetian RN, Kravchenko DV, Lomakin NV, Merkulova EA, Papazova NA, Pavlikova EP, Savchuk NP, Simakina EN, Sitdekov TA, Smolyarchuk EA, Tikhomolova EG, Yakubova EV, Ivachtchenko AV. AVIFAVIR for Treatment of Patients With Moderate Coronavirus Disease 2019 (COVID-19): Interim Results of a Phase II/III Multicenter Randomized Clinical Trial. Clin Infect Dis. 2021 Aug 2;73(3):531-534. doi: 10.1093/cid/ciaa1176. PMID: 32770240; PMCID: PMC7454388.
Katsura, H. et al. Human lung stem cell- based alveolospheres provide insights into SARS- CoV-2- mediated interferon responses and pneumocyte dysfunction. Cell Stem Cell 27, 890–904.e8 (2020).
Kaur, J. & Jain, S., 2012. Role of antigens and virulence factors od salmonella enterica serovar typhi in its pathogenesis. Microbiological research, 1(1), pp. 199-210.
Keputusan Menteri Kesehatan Republik Indonesia. Pedoman Pengendalian Demam Tifoid. Jakarta: Kementerian Kesehatan Republik Indonesia, 2006 http://www.pdpersi.co.id/peraturan/kepmenkes/kmk3642006.pdf
Keputusan Presiden Republik Indonesia No 17 Tahun 2023
Khurshid A, Rashid J. Clinical presentation of typhoid fever. Annals 2006;12;556-9
Kuehn R, Stoesser N, Eyre D, Darton TC, Basnyat B, Parry CM. Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins. Cochrane Database Syst Rev. 2022 Nov 24;11(11):CD010452. doi: 10.1002/14651858.CD010452.pub2. PMID: 36420914; PMCID: PMC9686137.
Manabe T, Kambayashi D, Akatsu H, Kudo K. Favipiravir for the treatment of patients with COVID-19: a systematic review and meta-analysis. BMC Infect Dis. 2021 May 27;21(1):489. doi: 10.1186/s12879-021-06164-x. PMID: 34044777; PMCID: PMC8159019.
Meiring JE, Khanam F, Basnyat B, Charles RC, Crump JA, Debellut F, Holt KE, Kariuki S, Mugisha E, Neuzil KM, Parry CM, Pitzer VE, Pollard AJ, Qadri F, Gordon MA. Typhoid fever. Nat Rev Dis Primers. 2023 Dec 14;9(1):71
Mirza SH, Beechmg NJ, Hart CA. Multi-drug resistant typhoid: a global problem. J Med Microbiol [Internet]. 1996 May 1;44(5):317–9. Available from: https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-44-5-317
Mochammad H, Mirjam B, Stella et al. Risk Factors for Clinical Typhoid Fever in Rural SouthSulawesi, Indonesia. International Journal of Tropical Medicine, 2009 4 (3) : 91-99
Nelwan, R., Chen Lie, K., Hadisaputro, S., Suwandoyo, E., Paramita, D. (2013). A Single Blind Comparative Randomized Non- Inferior Multicenter Study for Efficacy and Safety of Levofloxacin versus Ciprofloxacin in the Treatment of Uncomplicated Typhoid Fever. Advances in Microbiology, 03(01), 122–127. https://doi.org/10.4236/aim.2013.31019
Notarte, Kin Israel & Catahay, Jesus Alfonso & Velasco, Jacqueline & Pastrana, Adriel & Ver, Abbygail & Pangilinan, Flos & Peligro, Princess & Casimiro, Michael & Guerrero, Jonathan Jaime & Gellaco, Ma. Margarita Leticia & Lippi, Giuseppe & Henry, Brandon & Fernandez-de-las-Pe~nas, Cesar. (2022). Impact of COVID-19 vaccination on the risk of developing long-COVID and on existing long-COVID symptoms: A systematic review. eClinicalMedicine. 53. 10.1016/j.eclinm.2022.101624.
Nuruzzaman, Hilda, and Fariani Syahrul. "Risk Analysis of Typhoid Fever Based on Personal Hygiene and Street Food Consumption Habit at Home." Jurnal Berkala Epidemiologi, vol. 4, no. 1, 2016, pp. 74-86.
Pegues DA, Miller SI. Salmonellosis. In: Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J, eds. Harrison’s Principles of Internal Medicine. 19th edition. New York: McGraw Hill Education 2015.p.1049-55.
Punjabi NH, Agtini MD, Ochiai RL, et al. Enteric fever burden in North Jakarta, Indonesia: a prospective, community-based study. The Journal of Infection in Developing Countries 2013;7:781-7
Purwanti, Eka & Ronoatmojo, Sudarto. (2023). Association Between COVID-19 Vaccination Status With Severity of Confirmed COVID-19 Patients Period of January-July 2022 in Indonesia. Jurnal Ilmu Kesehatan Masyarakat. 14. 13-26. 10.26553/jikm.2023.14.1.13-26.
Raini, M. (2016). Fluoroquinolones Antibiotics: Benefit and Side Effects. Pusat Penelitian Dan Pengembangan Biomedis Dan Teknologi Dasar Kesehatan, Badan Litbangkes, Kemenkes RI, 26(3), 163–174.
Shin YR, Park KS, Cho KJ, Yoon TR. Bilateral septic arthritis of the hip caused by nontyphoidal salmonella: A case report. Acta Orthop Traumatol Turc. 2020 Mar;54(2):217-220. doi: 10.5152/j.aott.2020.02.278. PMID: 32254040; PMCID: PMC7286159.
Stokes EK, Zambrano LD, Anderson KN, Marder EP, Raz KM, El Burai Felix S, Tie Y, Fullerton KE. Coronavirus Disease 2019 Case Surveillance - United States, January 22-May 30, 2020. MMWR Morb Mortal Wkly Rep. 2020 Jun 19;69(24):759-765.
Thevarajan, Irani, K.L. Buising, B.C. Cowie, Clinical presentation and management of COVID-19, Med. J. Aust. 213 (3) (2020) 134–139.
Townsend JP, Hassler HB, Lamb AD, Sah P, Alvarez Nishio A, Nguyen C, Tew AD, Galvani AP, Dornburg A. Seasonality of endemic COVID-19. mBio. 2023 Dec 19;14(6):e0142623. doi: 10.1128/mbio.01426-23. Epub 2023 Nov 8. PMID: 37937979; PMCID: PMC10746271.
Tran HH, G. Bujune, B.M Nguyen, J.A Rottingen and RF Grais et al. Risk Factors Associated with Typhoid Fever in Son La Province, Northern Vietnam. Trans R. Soc. Trop. Med. Hyg, 2005;99:440-450
Tsai, Ping-Hsinga; Lai, Wei-Yia; Lin, Yi-Yinga; Luo, Yung-Hungb,c; Lin, Yi-Tsungc,d; Chen, Hsiao-Kangc,e; Chen, Yuh-Minb,c; Lai, Yi-Chunc,e; Kuo, Li-Chiaoc,e; Chen, Shew-Danc,e; Chang, Kao-Junga,c; Liu, Cheng-Hsuana,c; Chang, Shih-Chiehc,e,*; Wang, Fu-Derc,d,*; Yang, Yi-Pinga,c,f,*. Clinical manifestation and disease progression in COVID-19 infection. Journal of the Chinese Medical Association 84(1):p 3-8, January 2021. | DOI: 10.1097/JCMA.0000000000000463
Widoyono. 2011. Penyakit Tropis. Jakarta: Erlangga:36.
World Health Organization. Department of Immunization, Vaccines and Biologicals (IVB). Presented at SAGE meeting. Geneva, Switzerland: World Health Organization, Department of Immunization, Vaccines and Biologicals; April 4–7, 2022. https://terrance.who.int/mediacentre/data/ sage/SAGE_eYB_Apr2022.pdf
World Health Organization. Typhoid and other invasive Salmonellosis [Internet]. 2018 [cited 2018 Sep 5] Available from: https://www.who.int/immunization/ monitoring_surveillance/burden/vpd/WHO_SurveillanceVaccinePreventable_21_Typhoid_BW_R2.pdf?ua=1
Yasin, Nusrat & Jabeen, Azmat & Nisa, Iqbal & Tasleem, Umber & Khan, Hassan & Momin, Faiza & Shah, Faisal & Rasheed, Ubaid & Zeb, Umar & Safi, Aziz & Hussain, Mubbashir & Qasim, Muhammad & Rahman, Hazir. (2022). A review: Typhoid fever.
Yogo A, Yamamoto S, Iwamoto N, Aoki K, Motobayashi H, Tochitani K, Shimizu T. Non-typhoidal Salmonella bacteremia in COVID-19 with recrudescence of fever after corticosteroid discontinuation: A case report. IDCases. 2022;27:e01415. doi: 10.1016/j.idcr.2022.e01415. Epub 2022 Jan 21. PMID: 35096529; PMCID: PMC8779851.
Zhang T, Wu Q, Zhang Z. Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak. Curr Biol [Internet]. 2020;30(7):1346-1351.e2.
Zhao L, Zhong W. Mechanism of action of favipiravir against SARS-CoV-2: Mutagenesis or chain termination? Innovation (Camb). 2021 Nov 28;2(4):100165. doi: 10.1016/j.xinn.2021.100165. Epub 2021 Sep 8. PMID: 34518821; PMCID: PMC8425668.
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