Mikrobiota Usus dan Diabetes Mellitus Tipe 2: Sebuah Tinjauan Komprehensif
DOI:
https://doi.org/10.31004/jn.v9i1.38278Abstract
Diabetes melitus tipe 2 (DMT2) adalah penyakit metabolik yang sangat umum di seluruh dunia. Menurut studi terbaru, patofisiologi DMT2 berkaitan dengan keseimbangan mikrobiota usus. Tinjauan pustaka ini bertujuan untuk mengkaji hubungan antara mikrobiota usus dan DMT2, mengevaluasi jalur biologis yang mendasari, dan menyelidiki terapi berbasis mikrobiota. Melalui proses yang meliputi sintesis metabolit mikroba, peradangan sistemik, dan permeabilitas usus, mikrobiota usus memainkan peran penting dalam DMT2. Sensitivitas insulin dan kontrol glikemik dapat ditingkatkan dengan pendekatan terapi seperti transplantasi mikrobiota fekal (FMT), penggunaan probiotik, dan prebiotik. Meskipun temuan ini dapat memberikan informasi untuk strategi pencegahan dan pengobatan DMT2, penelitian lanjutan diperlukan untuk memahami mekanisme spesifik dan mengembangkan intervensi yang lebih efektif.
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Published
2024-12-06
How to Cite
Antoni, M. ., & Dharmawan, A. . (2024). Mikrobiota Usus dan Diabetes Mellitus Tipe 2: Sebuah Tinjauan Komprehensif. Jurnal Ners, 9(1), 1088–1094. https://doi.org/10.31004/jn.v9i1.38278
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