ANALISIS KESINTASAN 5 TAHUN PASIEN KANKER SERVIKS DI RSUD RADEN MATTAHER JAMBI TAHUN 2019- 2024
DOI:
https://doi.org/10.31004/jkt.v6i2.44682Abstract
Kanker serviks merupakan kanker kedua yang paling sering terjadi pada wanita dan merupakan penyebab utama kematian akibat kanker di kalangan wanita. Tingginya angka kejadian dan kematian akibat kanker serviks menunjukkan pentingnya analisis faktor-faktor yang mempengaruhi kesintasan pasien. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang memengaruhi ketahanan hidup pasien kanker serviks di RSUD Raden Mattaher Jambi. Penelitian dengan desain kohort retrospektif. Sampel penelitian terdiri dari 112 pasien kanker serviks di RSUD Raden Mattaher Jambi periode 2019-2024. Analisis data dilakukan secara univariat dan bivariat menggunakan Kaplan-Meier, uji Log-rank dan analisis Cox Proportional Hazard untuk mengetahui faktor-faktor yang memengaruhi risiko kematian. Faktor- faktor yang signifikan terhadap ketahanan hidup pasien kanker serviks umur (HR = 2,67; p = 0,036), ukuran tumor (HR = 2,67; p = 0,023), stadium kanker (HR = 5,79; p = 0,000), penyakit penyerta (HR = 3,19; p = 0,020), pendidikan (HR = 5,65; p = 0,000), status perkawinan (HR = 3,21; p = 0,004), dan pekerjaan (HR = 5,90; p = 0,001) dan faktor yang tidak signifikan jenis pengobatan (HR = 1,03; p = 0,905). Umur, ukuran tumor, stadium, penyakit penyerta, tingkat pendidikan, status perkawinan, dan status pekerjaan adalah faktor-faktor yang signifikan mempengaruhi kelangsungan hidup pasien kanker serviks di RSUD Raden Mattaher Jambi.References
Akinola, A., & Constance, M. S. (2021). Impact of educational intervention on cervical cancer screening uptake among reproductive age women. International Journal Of Community Medicine And Public Health, 8(4), 2053. https://doi.org/10.18203/2394-6040.ijcmph20211280
American Cancer Society. (2019). Cervical cancer causes, risk factors, and prevention risk factors. American Cancer Society, 2. https://www.cancer.org/cancer/cervical-cancer/causes-risks-prevention.html
Andinata, B., Bachtiar, A., Oktamianti, P., Partahi, J. R., & Dini, M. S. A. (2023). A Comparison of Cancer Incidences Between Dharmais Cancer Hospital and GLOBOCAN 2020: A Descriptive Study of Top 10 Cancer Incidences. Indonesian Journal of Cancer, 17(2), 119. https://doi.org/10.33371/ijoc.v17i2.982
Arbyn, M., Anttila, A., Jordan, J., Ronco, G., Schenck, U., Segnan, N., Wiener, H., Herbert, A., & von Karsa, L. (2010). European guidelines for quality assurance in cervical cancer screening. Second edition-summary document. Annals of Oncology, 21(3), 448–458. https://doi.org/10.1093/annonc/mdp471
Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424. https://doi.org/10.3322/caac.21492
Chen, Q., Zhao, J., Xue, X., & Xie, X. (2024). Effect of marital status on the survival outcomes of cervical cancer: a retrospective cohort study based on SEER database. BMC Women’s Health, 24(1), 1–11. https://doi.org/10.1186/s12905-024-02907-5
Di Asih I Maruddani. (2021). Survival analysis. In Survival Analysis. https://doi.org/10.1007/978-1-4614-4322-3_1
Endo, D., Todo, Y., Okamoto, K., Minobe, S., Kato, H., & Nishiyama, N. (2015). Prognostic factors for patients with cervical cancer treated with concurrent chemoradiotherapy: A retrospective analysis in a japanese cohort. Journal of Gynecologic Oncology, 26(1), 12–18. https://doi.org/10.3802/jgo.2015.26.1.12
Ferlay, J., Colombet, M., Soerjomataram, I., Parkin, D. M., Piñeros, M., Znaor, A., & Bray, F. (2021). Cancer statistics for the year 2020: An overview. International Journal of Cancer, 149(4), 778–789. https://doi.org/10.1002/ijc.33588
George T, J. (2021). Factors influencing utilization of cervical cancer screening services among women – A cross sectional survey. Clinical Epidemiology and Global Health, 11(February), 1–5. https://doi.org/10.1016/j.cegh.2021.100752
Hafildah, U., & Karisma, R. D. L. N. (2022). Analisis Ketahanan Hidup Pada Penderita Kanker Serviks Menggunakan Regresi Cox Proportional Hazard. Jurnal Riset Mahasiswa Matematika, 2(2), 59–67. https://doi.org/10.18860/jrmm.v2i2.15042
Hasankhani, M. B., Jahani, Y., Bazrafshan, A., Yazdizadeh, A., & Karamoozian, A. (2023). Factors Affecting Survival of Patients with Cervical Cancer. Iranian Journal of Public Health, 52(10), 2216–2224. https://doi.org/10.18502/ijph.v52i10.13860
Hsu, C., Lee, Y., & Chen, Y. (n.d.). Comorbidities and Survival in Cervical Cancer Patients: A Population-Based Study. 2016.
kementerian kesehatan RI, badan kebijakan pembagunan kesehatan. (2023). Survei Kesehatan Indonesia. Kementerian Kesehatan Republik Indonesia Tahun 2023, 01, 1–68.
Kementrian Kesehatan Republik Indonesia. (2024). Mengenal Apa itu Kanker Serviks. https://yankes.kemkes.go.id/view_artikel/3157/mengenal-apa-itu-kanker-serviks
Maria Benedictin Sandhi Cahyani, Abdul Khairul Rizki Purba, Asdi Wihandono, & Sri Purwaningsih. (2024). Relationship between comorbidity and mortality of stage IV breast cancer: A literature review. Magna Scientia Advanced Research and Reviews, 11(2), 385–395. https://doi.org/10.30574/msarr.2024.11.2.0138
Mastutik, G., Alia, R., Rahniayu, A., Kurniasari, N., Rahaju, A. S., & Mustokoweni, S. (2015). Skrining Kanker Serviks dengan Pemeriksaan Pap Smear di Puskesmas Tanah Kali Kedinding Surabaya dan Rumah Sakit Mawadah Mojokerto. Majalah Obstetri & Ginekologi, 23(2), 54. https://doi.org/10.20473/mog.v23i2.2090
Musa, J., Achenbach, C., & Dwyer, L. O. (2016). Pengpid, S., Peltzer, K., & Zhang, C. (2021). Uptake and correlates of cervical and breast cancer screening among women in Jordan: national results of the 2017-2018 Population and Family Health Survey. Gender and Behaviour, 19(2), 17751-17758.. PLoS ONE, 12(9), 1–6. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183924
Novalia, V. (2023). Kanker Serviks. GALENICAL : Jurnal Kedokteran Dan Kesehatan Mahasiswa Malikussaleh, 2(1), 45. https://doi.org/10.29103/jkkmm.v2i1.10134
Nubia Muñoz. (2010). Impact of human papillomavirus (HPV)-6/11/16/18 vaccine on all HPV-associated genital diseases in young women. https://pubmed.ncbi.nlm.nih.gov/?term=Muñoz+N&cauthor_id=20139221
Pinheiro, L. C., Reshetnyak, E., Akinyemiju, T., Phillips, E., & Safford, M. M. (2022). Social determinants of health and cancer mortality in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study. Cancer, 128(1), 122–130. https://doi.org/10.1002/cncr.33894
Rochayati, A. (2023). Hubungan Tingkat Pengetahuan Wus Terhadap Sikap Melakukan Deteksi Dini Kanker Leher Rahim Dengan Pemeriksaan Iva Di Puskesmas Pare Kecamatan Kranggan Kabupaten Temanggung Jawa Tengah. Sinar : Jurnal Kebidanan, 5(1), 41–51. https://doi.org/10.30651/sinar.v5i1.17555
Singh, D., Vignat, J., Lorenzoni, V., Eslahi, M., Ginsburg, O., Lauby-Secretan, B., Arbyn, M., Basu, P., Bray, F., & Vaccarella, S. (2023). Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. The Lancet Global Health, 11(2), e197–e206. https://doi.org/10.1016/S2214-109X(22)00501-0
Stanca, M., Căpîlna, D. M., & Căpîlna, M. E. (2022). Long-Term Survival, Prognostic Factors, and Quality of Life of Patients Undergoing Pelvic Exenteration for Cervical Cancer. Cancers, 14(9). https://doi.org/10.3390/cancers14092346
Teshome, R., Yang, I., Woldetsadik, E., Girma, E., Higgins, M., & Wells, J. (2024). Survival Status and Predictors Among Women with Advanced Stage of Cervical Cancer. International Journal of Women’s Health, 16, 605–617. https://doi.org/10.2147/IJWH.S455235
Timor-leste, I. (2021). Cervical Cancer Elimination Country review and roadmap for action. December, 4–7.
Wen, Y., Zhang, H., Zhi, K., & Li, M. (2022). Influence of marital status on the treatment and survival of middle-aged and elderly patients with primary bone cancer. Frontiers in Medicine, 9(October), 1–11. https://doi.org/10.3389/fmed.2022.1001522
WHO. (n.d.). Cervical cancer. 2022. https://www.who.int/news-room/fact-sheets/detail/cervical-cancer
Wiszniewska, M., Marcinkiewicz, A., Lipińska-Ojrzanowska, A., Kalska-Sochacka, K., & Walusiak-Skorupa, J. (2021). The Role Of Occupational Health Services In Cancer Prevention - Which Factors Determine The Implementation Of Preventive Measures? International Journal of Occupational Medicine and Environmental Health, 34(6), 723–736. https://doi.org/10.13075/IJOMEH.1896.01793
World health organisation. (2023). WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention use of mRNA tests for human papillomavirus (HPV).
Xu, Y., Zhang, S., & Zhao, J. (2024). Factors influencing the survival of cervical cancer. Theoretical and Natural Science, 46(1), 92–107. https://doi.org/10.54254/2753-8818/46/20240520
Y. Li et al. (2018). The impact of patient-centered care on quality of life and survival in cancer patients: a systematic review.
Yuan, R., Zhang, C., Li, Q., Ji, M., & He, N. (2021). The impact of marital status on stage at diagnosis and survival of female patients with breast and gynecologic cancers: A meta-analysis. Gynecologic Oncology, 162(3), 778–787. https://doi.org/10.1016/j.ygyno.2021.06.008
Zhang, S., Xu, H., Zhang, L., & Qiao, Y. (2020). Cervical cancer: Epidemiology, risk factors and screening. Chinese Journal of Cancer Research, 32(6), 720–728. https://doi.org/10.21147/j.issn.1000-9604.2020.06.05
Downloads
Published
Issue
Section
License
Copyright (c) 2025 ayu ipana Tarigan, Adelina Fitri, Hendra Dhermawan Sitanggang, Ummi Kalsum, Muhammad Syukri
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
