PEMANFAATAN CONTINUOUS GLUCOSE MONITORING (CGM) UNTUK MENGOPTIMALKAN MANAJEMEN DIABETES DAN KUALITAS HIDUP PASIEN: SYSTEMATIC LITERATURE REVIEW
DOI:
https://doi.org/10.31004/jkt.v6i2.43903Keywords:
CGM, Diabetes, Glukosa, HRQOL, MonitorAbstract
Diabetes merupakan masalah kesehatan yang banyak terjadi pada masyarakat Indonesia. Oleh karena itu perlu penanganan secara efektif untuk menghindari komplikasi lebih lanjut. Teknologi Continuous Glucose Monitoring (CGM) memungkinkan untuk memantau kadar gula darah secara real time, sehingga membantu pasien mengelola diabetes dan kualitas hidup. Penelitian ini bertujuan untuk mengevaluasi efektivitas dan manfaat CGM dalam mengoptimalkan manajemen diabetes serta kualitas hidup pasien. Metode yang digunakan yaitu Systematic Literature Review (SLR) dengan pendekatan PRISMA. Artikel diperoleh dari database PubMed, Sciencedirect, dan Semantic Scholar yang relevan dalam rentang waktu 2020-2025. Dari 6428 artikel yang teridentifikasi, setelah penyaringan terdapat 10 jurnal yang sesuai dengan kriteria inklusi. Tinjauan sistematis ini mengungkapkan bahwa CGM dapat memperbaiki manajemen glukosa, menurunkan hipoglikemia, dan meningkatkan efektivitas terapi. CGM juga bermanfaat bagi ibu hamil dengan diabetes gestasional dan pasien dengan gangguan penglihatan. Selain itu, CGM lebih efektif dibandingkan dengan SMBG dalam kontrol glikemik dan kenyamanan pasien, meskipun biayanya lebih tinggi. Namun, dalam kasus tertentu seperti diabetes gestasional ringan, SMBG masih menjadi alternatif dengan biaya lebih rendah. Terdapat hambatan dalam penggunaan professional Continuous Glucose Monitoring (pCGM) yaitu risiko hipoglikemia yang tidak berkurang drastis, serta kesulitan mengunduh data berbasis cloud, sehingga diperlukan kolaborasi dengan tim IT. Teknologi CGM terbukti efektif dalam mengelola kadar glukosa dan kualitas hidup pasien diabetes. Meskipun masih terdapat tantangan dalam implementasi teknologi ini yang perlu mendapat dukungan dan integrasi sistem layanan kesehatan.References
Ajjan, R. A., Heller, S. R., Everett, C. C., Vargas-Palacios, A., Higham, R., Sharples, L., Gorog, D. A., Rogers, A., Reynolds, C., Fernandez, C., Rodrigues, P., Sathyapalan, T., Storey, R. F., & Stocken, D. D. (2023). Multicenter Randomized Trial of Intermittently Scanned Continuous Glucose Monitoring Versus Self-Monitoring of Blood Glucose in Individuals With Type 2 Diabetes and Recent-Onset Acute Myocardial Infarction: Results of the LIBERATES Trial. Diabetes Care, 46(2), 441–449. https://doi.org/10.2337/dc22-1219
Akturk, H. K., Snell-Bergeon, J. K., & Shah, V. N. (2021). Continuous Glucose Monitor with Siri Integration Improves Glycemic Control in Legally Blind Patients with Diabetes. Diabetes Technology and Therapeutics, 23(1), 81–83. https://doi.org/10.1089/dia.2020.0320
Allen, N. A., Berg, C. A., Iacob, E., Gonzales, B. R., Butner, J. E., & Litchman, M. L. (2024). Examining Share plus—A Continuous Glucose Monitoring Plus Data-Sharing Intervention in Older Adults and Their Care Partners: Protocol for a Randomized Control Study. JMIR Research Protocols, 13. https://doi.org/10.2196/60004
Antar, S. A., Ashour, N. A., Sharaky, M., Khattab, M., Ashour, N. A., Zaid, R. T., Roh, E. J., Elkamhawy, A., & Al-Karmalawy, A. A. (2023). Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments. In Biomedicine and Pharmacotherapy (Vol. 168). Elsevier Masson s.r.l. https://doi.org/10.1016/j.biopha.2023.115734
Bergenstal, R. M., Layne, J. E., Zisser, H., Gabbay, R. A., Barleen, N. A., Lee, A. A., Majithia, A. R., Parkin, C. G., & Dixon, R. F. (2021). Remote Application and Use of Real-Time Continuous Glucose Monitoring by Adults with Type 2 Diabetes in a Virtual Diabetes Clinic. Diabetes Technology and Therapeutics, 23(2), 128–132. https://doi.org/10.1089/dia.2020.0396
Cabrera, D., Cabrera, L., & Cabrera, E. (2023). The Steps to Doing a Systems Literature Review (SLR). https://doi.org/10.54120/jost.pr000019.v1
Champakanath, A., Akturk, H. K., Alonso, G. T., Snell-Bergeon, J. K., & Shah, V. N. (2022). Continuous Glucose Monitoring Initiation Within First Year of Type 1 Diabetes Diagnosis Is Associated With Improved Glycemic Outcomes: 7-Year Follow-Up Study. Diabetes Care, 45(3), 750–753. https://doi.org/10.2337/dc21-2004
Databoks. (2021). Kasus Kematian Akibat Diabetes di Indonesia Terbesar Keenam di Dunia. Jakarta: Katadata.co.id.
Dillmann, C., Amoura, L., Fall Mostaine, F., Coste, A., Bounyar, L., & Kessler, L. (2022). Feasibility of Real-Time Continuous Glucose Monitoring Telemetry System in an Inpatient Diabetes Unit: A Pilot Study. Journal of Diabetes Science and Technology, 16(4), 955–961. https://doi.org/10.1177/1932296821994586
Durnwald, C., Beck, R. W., Li, Z., Norton, E., Bergenstal, R. M., Johnson, M., Dunnigan, S., Banfield, M., Krumwiede, K., Sibayan, J., Calhoun, P., & Carlson, A. L. (2024). Continuous Glucose Monitoring Profiles in Pregnancies With and Without Gestational Diabetes Mellitus. Diabetes Care, 47(8), 1333–1341. https://doi.org/10.2337/dc23-2149
Elsayed, N. A., Aleppo, G., Aroda, V. R., Bannuru, R. R., Brown, F. M., Bruemmer, D., Collins, B. S., Hilliard, M. E., Isaacs, D., Johnson, E. L., Kahan, S., Khunti, K., Kosiborod, M., Leon, J., Lyons, S. K., Murdock, L., Perry, M. Lou, Prahalad, P., Pratley, R. E., … Gabbay, R. A. (2023). 2. Classification and Diagnosis of Diabetes: Standards of Care in Diabetes—2023. Diabetes Care, 46, S19–S40. https://doi.org/10.2337/dc23-S002
Guideline, N. I. C. E. (2023). Description of technology. National Health Services.
Isaacson, B., Kaufusi, S., Sorensen, J., Joy, E., Jones, C., Ingram, V., Mark, N., Phillips, M., & Briesacher, M. (2022). Demonstrating the Clinical Impact of Continuous Glucose Monitoring Within an Integrated Healthcare Delivery System. Journal of Diabetes Science and Technology, 16(2), 383–389. https://doi.org/10.1177/1932296820955228
Lai, M., Weng, J., Yang, J., Gong, Y., Fang, F., Li, N., Kang, M., Xu, X., & Wang, Y. (2023). Effect of continuous glucose monitoring compared with self-monitoring of blood glucose in gestational diabetes patients with HbA1c<6%: a randomized controlled trial. Frontiers in Endocrinology, 14. https://doi.org/10.3389/fendo.2023.1174239
Lambrinou, E., Hansen, T. B., & Beulens, J. W. J. (2019). Lifestyle factors, self-management and patient empowerment in diabetes care. European Journal of Preventive Cardiology, 26(2_suppl), 55–63. https://doi.org/10.1177/2047487319885455
Lee, S., Lee, S., Kim, K. M., & Shin, J. H. (2023). Usefulness of continuous glucose monitoring of blood glucose control in patients with diabetes undergoing hemodialysis: A pilot study. Frontiers in Medicine, 10. https://doi.org/10.3389/fmed.2023.1145470
McLean, A., Barr, E., Tabuai, G., Murphy, H. R., & Maple-Brown, L. (2023). Continuous Glucose Monitoring Metrics in High-Risk Pregnant Women with Type 2 Diabetes. Diabetes Technology and Therapeutics, 25(12), 836–844. https://doi.org/10.1089/dia.2023.0300
Patel, R., Schoen, R., & Litten, K. (2024). Diabetes technology: Continuous glucose monitoring and the role of ambulatory care pharmacists. JAPhA Practice Innovations, 1(1), 100005. https://doi.org/10.1016/j.japhpi.2023.100005
Reaven, P. D., Newell, M., Rivas, S., Zhou, X., Norman, G. J., & Zhou, J. J. (2023). Initiation of Continuous Glucose Monitoring Is Linked to Improved Glycemic Control and Fewer Clinical Events in Type 1 and Type 2 Diabetes in the Veterans Health Administration. Diabetes Care, 46(4), 854–863. https://doi.org/10.2337/dc22-2189
Simonson, G. D., Bergenstal, R. M., Johnson, M. L., Davidson, J. L., & Martens, T. W. (2021). Effect of Professional CGM (pCGM) on Glucose Management in Type 2 Diabetes Patients in Primary Care. Journal of Diabetes Science and Technology, 15(3), 539–545. https://doi.org/10.1177/1932296821998724
Tomic, D., Shaw, J. E., & Magliano, D. J. (2022). The burden and risks of emerging complications of diabetes mellitus. In Nature Reviews Endocrinology (Vol. 18, Issue 9, pp. 525–539). Nature Research. https://doi.org/10.1038/s41574-022-00690-7
Twigg, S., Lim, S., Yoo, S. H., Chen, L., Bao, Y., Kong, A., Yeoh, E., Chan, S. P., Robles, J., Mohan, V., Cohen, N., McGill, M., & Ji, L. (2023). Asia-Pacific Perspectives on the Role of Continuous Glucose Monitoring in Optimizing Diabetes Management. In Journal of Diabetes Science and Technology. SAGE Publications Inc. https://doi.org/10.1177/19322968231176533
WHO. (2024). Urgent action needed as global diabetes cases increase four-fold over past decades. World Health Organization.
Zheng, M., Luo, Y., Lin, W., Khoja, A., He, Q., Yang, S., Zhao, X., & Hu, P. (2020). Comparing effects of continuous glucose monitoring systems (CGMs) and self-monitoring of blood glucose (SMBG) amongst adults with type 2 diabetes mellitus: A systematic review protocol. Systematic Reviews, 9(1). https://doi.org/10.1186/s13643-020-01386-7
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