KARDIOMIOPATI HIPERTROFI: SEBUAH TINJAUAN PUSTAKA

Authors

  • Siti Nurhaliza Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Saskia Safarinaa Hazaa Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Ahmad Nur Rifa'i Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Amila Fadila Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Kadek Nandita Nugraha Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Muhammad Zaim Muflih Syamsuddin Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Rosita Wenilia Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Najla Aulia Yahya Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Rifky Sandya Rakadi Putra Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Sofia Kadarisma Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia
  • Siska Dwi Safira Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Nusa Tenggara Barat, Indonesia

DOI:

https://doi.org/10.31004/jkt.v5i4.36755

Keywords:

EKG, Kardiomiopati hipertrofi, Left Ventricle Outflow Tract, Mutasi gen

Abstract

Kardiomiopati hipertrofi (HCM) adalah kelainan genetik miosit jantung yang mengakibatkan hipertrofi ventrikel kiri, fibrosis dan hiperkontraktilitas jantung. Kelainan ini diduga akibat mutasi gen sarkomer dominan autosomal. dan merupakan penyebab kematian mendadak paling sering pada usia muda. Berdasarkan data ekokardiografi yang berasal dari Amerika Serikat teridentifikasi sebanyak 0.2% dari keseluruhan populasi menderita kardimiopati hipertrofi. Penelitian ini menggunakan pendekatan tinjauan literatur dengan mengumpulkan data dari basis data online seperti PubMed, ScienceDirect, MDPI, dan Google Scholar. Tinjauan literatur ini secara komprehensif membahas definisi, etiologi, epidemiologi, faktor risiko, patofisiologi, diagnosis, tatalaksana, komplikasi dan prognosis kardiomiopati hipertrofi.

References

Andrianto, & Sukmawati, I. (2020). Penyakit Jantung Struktural. In Andrianto & A. Subagjo (Eds.), Penyakit Jantung Struktural. Departemen - SMF Penyakit Kardiologi dan Kedokteran Vaskular Fakultas Kedokteran Univesitas Airlangga.

Antunes, M. de O., & Scudeler, T. L. (2020). Hypertrophic cardiomyopathy. IJC Heart & Vasculature, 27, 100503. https://doi.org/10.1016/j.ijcha.2020.100503

Bhandari, A., Shah, B., Mahaseth, A., & Sharma, S. K. (2019). Stroke in young secondary to infective endocarditis complicating hypertrophic cardiomyopathy – A case report. Nepalese Heart Journal, 16(1), 57–59. https://doi.org/10.3126/njh.v16i1.23904

Elliott, P. M., Anastasakis, A., Borger, M. A., Borggrefe, M., & Cecchi, F. (2014). 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy. European Heart Journal, 35(39), 2733–2779. https://doi.org/10.1093/eurheartj/ehu284

Harper, A. R., Goel, A., Grace, C., Thomson, K. L., Petersen, S. E., Xu, X., Waring, A., Ormondroyd, E., Kramer, C. M., Ho, C. Y., Neubauer, S., Kolm, P., Kwong, R., Dolman, S. F., Desvigne-Nickens, P., Dimarco, J. P., Geller, N., Kim, D.-Y., Zhang, C., … Watkins, H. (2021). Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Nature Genetics, 53(2), 135–142. https://doi.org/10.1038/s41588-020-00764-0

Lilly, L. S. (2019). Patofisiologi Penyakit Jantung (6th ed.). Medik - Jakarta.

Lioncino, M., Monda, E., Verrillo, F., Moscarella, E., Calcagni, G., Drago, F., Marino, B., Digilio, M. C., Putotto, C., Calabrò, P., Russo, M. G., Roberts, A. E., Gelb, B. D., Tartaglia, M., & Limongelli, G. (2022). Hypertrophic Cardiomyopathy in RASopathies. Heart Failure Clinics, 18(1), 19–29. https://doi.org/10.1016/j.hfc.2021.07.004

Marian, A. J., & Braunwald, E. (2017). Hypertrophic Cardiomyopathy. Circulation Research, 121(7), 749–770. https://doi.org/10.1161/CIRCRESAHA.117.311059

Maron, B. J., Desai, M. Y., Nishimura, R. A., Spirito, P., Rakowski, H., Towbin, J. A., Dearani, J. A., Rowin, E. J., Maron, M. S., & Sherrid, M. V. (2022). Management of Hypertrophic Cardiomyopathy. Journal of the American College of Cardiology, 79(4), 390–414. https://doi.org/10.1016/j.jacc.2021.11.021

Maron, B. J., Desai, M. Y., Nishimura, R. A., Spirito, P., Rakowski, H., Towbin, J. A., Rowin, E. J., Maron, M. S., & Sherrid, M. V. (2022). Diagnosis and Evaluation of Hypertrophic Cardiomyopathy. Journal of the American College of Cardiology, 79(4), 372–389. https://doi.org/10.1016/j.jacc.2021.12.002

Ommen, S. R., Mital, S., Burke, M. A., Day, S. M., Deswal, A., Elliott, P., Evanovich, L. L., Hung, J., Joglar, J. A., Kantor, P., Kimmelstiel, C., Kittleson, M., Link, M. S., Maron, M. S., Martinez, M. W., Miyake, C. Y., Schaff, H. V., Semsarian, C., & Sorajja, P. (2020). 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: Executive Summary. Circulation, 142(25). https://doi.org/10.1161/CIR.0000000000000938

Park, Y. M. (2023). Updated risk assessments for sudden cardiac death in hypertrophic cardiomyopathy patients with implantable cardioverter-defibrillator. The Korean Journal of Internal Medicine, 38(1), 7–15. https://doi.org/10.3904/kjim.2022.144

Robyns, T., Nuyens, D., Lu, H. R., Gallacher, D. J., Vandenberk, B., Garweg, C., Ector, J., Pagourelias, E., Van Cleemput, J., Janssens, S., & Willems, R. (2018). Prognostic value of electrocardiographic time intervals and QT rate dependence in hypertrophic cardiomyopathy. Journal of Electrocardiology, 51(6), 1077–1083. https://doi.org/10.1016/j.jelectrocard.2018.09.005

Teekakirikul, P., Zhu, W., Huang, H. C., & Fung, E. (2019). Hypertrophic Cardiomyopathy: An Overview of Genetics and Management. Biomolecules, 9(12), 878. https://doi.org/10.3390/biom9120878

Tuohy, C. V., Kaul, S., Song, H. K., Nazer, B., & Heitner, S. B. (2020). Hypertrophic cardiomyopathy: the future of treatment. European Journal of Heart Failure, 22(2), 228–240. https://doi.org/10.1002/ejhf.1715

Downloads

Published

2024-11-26

How to Cite

Nurhaliza, S., Hazaa, S. S., Nur Rifa’i, A. ., Fadila, A. ., Nugraha, K. N. ., Syamsuddin, M. Z. M. ., Wenilia, R. ., Yahya, N. A. ., Putra, R. S. R., Kadarisma, S. ., & Safira, S. D. . (2024). KARDIOMIOPATI HIPERTROFI: SEBUAH TINJAUAN PUSTAKA. Jurnal Kesehatan Tambusai, 5(4), 11093–11098. https://doi.org/10.31004/jkt.v5i4.36755

Issue

Vol. 5 No. 4 (2024): DESEMBER 2024

Section

Articles

License

Copyright (c) 2024 Siti Nurhaliza, Saskia Safarinaa Hazaa, Ahmad Nur Rifa'i, Amila Fadila, Kadek Nandita Nugraha, Muhammad Zaim Muflih Syamsuddin, Rosita Wenilia, Najla Aulia Yahya, Rifky Sandya Rakadi Putra, Sofia Kadarisma, Siska Dwi Safira

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).