ADENOCARCINOMA TUMOR IN THE CEREBELLUM AS METASTASIS FROM LUNG CANCER WITH KLEBSIELLA OXYTOCA WITHIN THE TUMOR: A CASE REPORT
DOI:
https://doi.org/10.31004/jkt.v5i4.34198Keywords:
Metastatic adenocarcinoma, cerebellar metastasis, lung cancer, Klebsiella oxytoca, case reportAbstract
Laporan kasus ini merinci kejadian langka metastasis serebelar akibat kanker paru-paru, yang dipersulit oleh infeksi intratumoral Klebsiella oxytoca pada pria berusia 57 tahun dengan riwayat perokok berat. Pasien awalnya mengalami vertigo persisten, tidak responsif terhadap pengobatan standar. Pemindaian MRI menunjukkan massa serebelar dengan peningkatan kontras, disertai massa paru multipel. Tes darah menunjukkan leukositosis, anemia, dan peningkatan jumlah neutrofil, menunjukkan adanya infeksi aktif. Evaluasi patologis selanjutnya pada tumor serebelar memastikan adanya adenokarsinoma metastatik, dengan temuan tambahan infeksi Klebsiella oxytoca di dalam jaringan tumor. Mengingat diagnosis ganda adenokarsinoma metastatik dan infeksi bakteri sekunder, pasien menjalani operasi trepanasi darurat untuk mengurangi tekanan dan mengangkat tumor. Terapi antibiotik yang ditargetkan dimulai untuk mengatasi infeksi, diikuti dengan pemantauan pasca operasi yang berkelanjutan. Strategi pengobatan komprehensif ini menghasilkan perbaikan signifikan pada gejala pasien, khususnya resolusi vertigo, dan peningkatan kualitas hidup secara keseluruhan. Kasus ini menyoroti pentingnya pemeriksaan diagnostik menyeluruh dan pendekatan multidisiplin ketika menangani kasus kompleks yang melibatkan tumor otak metastatik dengan komplikasi infeksi sekunder. Identifikasi dini agen infeksi, bersama dengan intervensi bedah yang cepat dan terapi yang ditargetkan, sangat penting untuk mengoptimalkan hasil pasien dan meningkatkan prognosis jangka panjang dalam skenario klinis yang jarang dan menantang.References
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