CASE REPORT : EFEK PENGGUNAAN LOW DOSE KETAMIN 0,5 MG IV TERHADAP TERHADAP KEJADIAN POST AND PONV PASKA INSERSI LMA

Authors

Riska Rianti Program Profesi Dokter. Fakultas Kedokteran Universitas Muslim Indonesia
Fendy Dwimartyono Departemen Bagian Ilmu Anestesiologi. Fakultas Kedokteran Universitas Muslim Indonesia
Muh. Nur Abadi Departemen Bagian Ilmu Anestesiologi. Fakultas Kedokteran Universitas Muslim Indonesia

DOI:

https://doi.org/10.31004/jkt.v5i3.30772

Keywords:

Ketamine, Laryngeal Mask Airway, Post Operative nausea and vomiting, postoperative sore throat

Abstract

Pendekatan multimodal analgesik non-opioid atau Opioid Free Anastesia (OFA) ditujukan untuk mengoptimalkan opsi tambahan intraoperatif, Beberapa meta-analisis juga telah melaporkan efek menguntungkan dari ketamine pada proses pemulihan pasca operatif. ketamin dosis tinggi dilaporkan menyebabkan berbagai efek buruk dan harus dihindari. Namun, Pemberian ketamine dosis subanestesi 0,1-0,5 mg/kg IV merupakan salah satu obat yang dapat menggantikan opioid sebagai analgetik dengan memberikan efek samping minimal. Kami melaporkan 6 kasus dengan diagnosis yang berbeda yang direncanakan tindakan operatif yang dikelola dengan anastesi umum dengan Laryngeal Mask Airway (LMA) dan menggunakan ketamin dosis rendah 0,5 mg/kgBB IV sebagai pengganti Opioid yaitu fentanyl. Setelah dilakukan insersi LMA dan pada proses pemulihan pasca operatif didapatkan hasil berupa efek Postoperatif Nausea and Vomiting (PONV) yang minimal dimana rata rata kasus mendapat skor 0 atau tidak mengalami mual maupun muntah, dan pada Postoperative Sore Throat (POST) score didapatkan hasil rata – rata skor nol dimana tidak ada yang mengalami nyeri maupun keluhan terkait tenggorokannya

References

Belete, E., W/Yahones, M., Aweke, Z., Dendir, G., Mola, S., Neme, D., Melaku, G., Ahmed, S., Regasa, T., & Tesfaye, B. (2021). Comparison Of Thiopentone With Lidocaine Spray Vs Propofol For Laryngeal Mask Airway Insertion At Tikur Anbessa Specialized Hospital. A Prospective Cohort Study. Annals Of Medicine And Surgery, 66. Https://Doi.Org/10.1016/J.Amsu.2021.102436

Bell, R. F., & Kalso, E. A. (2018). Ketamine For Pain Management. Pain Reports, 3(5). Https://Doi.Org/10.1097/PR9.0000000000000674

Beloeil, H. (2019). Opioid-Free Anaesthesia: The Need For Evidence-Based Proofs. Https://Doi.Org/10.1016/J.Accpm.2019.05.002ï

Budiarta, I. G. (2019). Ketamin [Universitas Udayana]. Https://Www.S3ilmukedokteranunud.Org/Wp-Content/Uploads/2021/01/MKPD-KETAMIN.Pdf

Charan, S., Khilji, Mohd. Y., Jain, R., Devra, V., & Saxena, M. (2018). Inhalation Of Ketamine In Different Doses To Decrease The Severity Of Postoperative Sore Throat In Surgeries Under General Anesthesia Patients. Anesthesia: Essays And Researches, 12(3), 625. Https://Doi.Org/10.4103/Aer.Aer_65_18

Chia, P. A., Cannesson, M., & Bui, C. C. M. (2020). Opioid Free Anesthesia: Feasible? In Current Opinion In Anaesthesiology (Vol. 33, Issue 4, Pp. 512–517). Lippincott Williams And Wilkins. Https://Doi.Org/10.1097/ACO.0000000000000878

Dutt, A., Joad, A. K., & Sharma, M. (2012). Induction For Classic Laryngeal Mask Airway Insertion: Does Low-Dose Fentanyl Work. Journal Of Anaesthesiology Clinical Pharmacology, 28(2), 210–213. Https://Doi.Org/10.4103/0970-9185.94877

Dwivedi, M. B., Puri, A., Dwivedi, S., & Deol, H. (2018). Role Of Opioids As Coinduction Agent With Propofol And Their Effect On Apnea Time, Recovery Time, And Sedation Score. International Journal Of Critical Illness And Injury Science, 8(1), 4–8. Https://Doi.Org/10.4103/IJCIIS.IJCIIS_4_17

Eidan, A., Ratsch, A., Burmeister, E. A., & Griffiths, G. (2020). Comparison Of Opioid-Free Anesthesia Versus Opioid-Containing Anesthesia For Elective Laparoscopic Surgery (Cofa: Lap): A Protocol Measuring Recovery Outcomes. Methods And Protocols, 3(3), 1–13. Https://Doi.Org/10.3390/Mps3030058

Farazmehr, Kourosh, Aryafar, M., Gholami, F., Dehghanmanshadi, G., & Hosseini, S. S. (2021). A Prospective Study On The Incidence Of Sore Throat After Use Of Laryngeal Mask Airway During General Anesthesia. Annals Of Medicine And Surgery, 68. Https://Doi.Org/10.1016/J.Amsu.2021.102595

Ferraro, M. C., Cashin, A. G., O’Connell, N. E., Visser, E. J., Abdel Shaheed, C., Wewege, M. A., Gustin, S. M., & Mcauley, J. H. (2023). Ketamine And Other NMDA Receptor Antagonists For Chronic Pain. Cochrane Database Of Systematic Reviews, 2023(3). Https://Doi.Org/10.1002/14651858.CD015373

Karnina, R., & Ismah, M. N. (2021). Gambaran Kejadian Postoperative Nausea And Vomiting (PONV) Pada Pasien Pasca Tindakan Dilatasi Kuretase Dengan Anestesi Umum Di RSIA B Pada Tahun 2019. Muhammadiyah Journal Of Midwifery, 2(1), 10. Https://Doi.Org/10.24853/Myjm.2.1.10-20

Léger, M., Pessiot-Royer, S., Perrault, T., Parot-Schinkel, E., Costerousse, F., Rineau, E., & Lasocki, S. (2021). The Effect Of Opioid-Free Anesthesia Protocol On The Early Quality Of Recovery After Major Surgery (SOFA Trial): Study Protocol For A Prospective, Monocentric, Randomized, Single-Blinded Trial. Trials, 22(1). Https://Doi.Org/10.1186/S13063-021-05829-X

Obsa, M. S., Adem, A. O., Bancha, B., Gelgelu, T. B., Gemechu, A. D., Tilla, M., Nugusse, M. A., Wosene, N. G., Gobena, N., Hamu, A., & Abdulkadir, S. (2022). Global Incidence And Risk Factors Of Post-Operative Sore Throat Among Patients Who Underwent Surgery: A Systematic Review And Meta-Analysis. In International Journal Of Surgery Open (Vol. 47). Elsevier Ltd. Https://Doi.Org/10.1016/J.Ijso.2022.100536

Park, S. Y., Kim, S. H., Noh, J. Il, Lee, S. M., Kim, M. G., Kim, S. H., Ok, S. Y., & Kim, S. I. (2010). The Effect Of Intravenous Low Dose Ketamine For Reducing Postoperative Sore Throat. Korean Journal Of Anesthesiology, 59(1), 22–26. Https://Doi.Org/10.4097/Kjae.2010.59.1.22

Pratama, A., Pradian, E., & Erlangga, E. (2020). Perbandingan Efek Fentanil Dengan Ketamin Terhadap Skor Pemulihan Pascaanestesi Umum Diukur Dengan Qor-40 Serta Perubahan Tekanan Darah Dan Nadi Pada Operasi Odontektomi. Jurnal Anastesi Perioperatif, 8(38), 57–149. Https://Doi.Org/10.15851/Jap.V8n3.0000

Sheikhzade, D., Razaghipour, M., Seyedhejazi, M., Aliakbari Sharabiani, B., & Marahem, M. (2020). A Comparison Of The Sevoflurane And Total Intravenous Anesthesia On The Quality Of Recovery In 2 To 10-Year-Old Children. Iranian Journal Of Pediatrics, 31(1). Https://Doi.Org/10.5812/Ijp.105900

Wiryana, M., Sinardja, I. K., Budiart, I. G., Senapathi, T. G. A., Widnyana, M., Aryabiantara, I. W., Agung Gede Utara Hartawan, I. G., Parami, P., Novita Pradnyani, N. P., & Pradhana, A. P. (2017). Low Dose Ketamin. Bali Journal Of Anesthesiology, 1(1), 13–19. Https://Doi.Org/10.15562/Bjoa.V1i1.4

Downloads

Published

2024-08-01

Issue

Vol. 5 No. 3 (2024): SEPTEMBER 2024

Section

Articles

License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the workâ€™s authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journalâ€™s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).