Profil Spesies Candida Dan Pola Kepekaan Antijamur Pada Pasien Candidemia Darah di Unit Mikrobiologi Klinik RSUD Dr.Soetomo periode 2020-2023
DOI:
https://doi.org/10.31004/jkt.v5i1.23799Keywords:
Candida spp, candidemia, infectionAbstract
Candida spp fungal infections. can attack the circulatory system (can be known as candidemia or blood infection by the fungus Candida spp.). Patients in the intensive care unit (ICU) or emergency unit (IGD) with long-term air-conditioned conditions resulting in Candida spp. can grow more easily and increase the risk of fungal infections. This study aims to evaluate the profile of Candida spp. as well as patterns of sensitivity to antifungals in patients with blood candidemia in the Clinical Microbiology Unit of Dr. RSUD. Soetomo during the 2020-2023 period. This research method involves analysis of medical record data of patients diagnosed with blood candidemia, with a retrospective descriptive research type. The research samples were isolate data, used were clinical specimens that can cause candidiasis in the vagina, oral cavity and urogenital tract. The sample size in this study was as large as the data from isolates originating from a total of clinics in the time period. The results of this study provide a comprehensive picture regarding the distribution of Candida spp. the most commonly encountered, as well as the pattern of sensitivity to certain antifungals in patients with blood candidemia in the Dr. Hospital environment. Soetomo. It is hoped that the information obtained from this study will provide better guidance in the management and selection of appropriate therapy for patients affected by blood candidemia in the future.References
Behzadi, P., Behzadi, E., & Ranjbar, R. (2015). Urinary tract infections and candida albicans. Central European Journal of Urology, 68(1), 96–101. https://doi.org/10.5173/ceju.2015.01.474
Bhatt, V. R., Viola, G. M., & Ferrajoli, A. (2011). Invasive fungal infections in acute leukemia. Therapeutic Advances in Hematology, 2(4), 231–247. https://doi.org/10.1177/2040620711410098
Cangui-Panchi, S. P., Ñacato-Toapanta, A. L., Enríquez-Martínez, L. J., Salinas-Delgado, G. A., Reyes, J., Garzon-Chavez, D., & Machado, A. (2023). Battle royale: Immune response on biofilms – host-pathogen interactions. Current Research in Immunology, 4(March). https://doi.org/10.1016/j.crimmu.20 23.100057
D’Enfert, C., Kaune, A. K., Alaban, L. R., Chakraborty, S., Cole, N., Delavy, M., Kosmala, D., Marsaux, B., Fróis-Martins, R., Morelli, M., Rosati, D., Valentine, M., Xie, Z., Emritloll, Y., Warn, P. A., Bequet, F., Bougnoux, M. E., Bornes, S., Gresnigt, M. S., … Brown, A. J. P. (2021). The impact of the fungus-host-microbiota interplay upon Candida albicans infections: Current knowledge and new perspectives. In FEMS Microbiology Reviews (Vol. 45, Issue 3). https://doi.org/10.1093/femsre/fuaa060
Eggimann, P., & Pittet, D. (2014). Candida colonization index and subsequent infection in critically ill surgical patients: 20 years later. Intensive Care Medicine, 40(10), 1429–1448. https://doi.org/10.1007/s00134-014-3355-z
Elsayed, H., Shaker, H., Whittle, I., & Hussein, S. (2012). The impact of systemic fungal infection in patients with perforated oesophagus. Annals of the Royal College of Surgeons of England, 94(8), 579–584. https://doi.org/10.1308/003588412X13373405388095
Gatot, D. (2016). Infeksi Jamur Sistemik pada Pasien Immunocompromised. Sari Pediatri, 3(4), 242. https://doi.org/10.14238/sp3.4.2002.242-6
Macias-Paz, I. U., Pérez-Hernández, S., Tavera-Tapia, A., Luna-Arias, J. P., Guerra-Cárdenas, J. E., & Reyna-Beltrán, E. (2023). Candida albicans the main opportunistic pathogenic fungus in humans. Revista Argentina de Microbiologia, 55(2), 189–198. https://doi.org/10.1016/j.ram.2022.08.003
Mario, D. A. N., Denardi, L. B., Bandeira, L. A., Antunes, M. S., Santurio, J. M., Severo, L. C., & Alves, S. H. (2012). The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates. Memorias Do Instituto Oswaldo Cruz, 107(3), 433–436. https://doi.org/10.1590/S0074-02762012000300022
Mursinah, Ibrahim F, W. M. (2016). Profil Candida penyebab Candidemia dan pola kepekaan terhadap antijamur pada pasien kritis di RSCM. Jurnal Biotek Medisiana Indonesia, 5, 105–111.
Reza, N. R., Shw, T., Basuki, S., Smf, D., Kesehatan, I., Universitas, F. K., & Malang, S. A. (2017). Uji Kepekaan In Vitro Flukonazol Terhadap Spesies Candida penyebab Candidiasis Oral Pada Pasien HIV / AIDS dengan Vitek II ( In Vitro Susceptibilty Test of Fluconazole to Candida spp in Patients with Oropharyngeal Candidiasis and HIV / AIDS with Vitek II. Berkala Ilmu Kesehatan Kulit Dan Kelamin, 29(3), 43–47. https://doi.org/1 0.1175/2008JTECHA1150.1
Salman, W. O., Haya, L. O. M. Y., Binekada, I. M. C., Fristiohady, A., & Alifariki, L. O. (2021). Potret Masyarakat Pesisir. Deepublish.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Wardatun Faizah, Nurul Wiqoyah, Evy Ervianti, Pepy Dwi Endraswari
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).