HUBUNGAN ANTARA KEJADIAN CARPAL TUNNEL SYNDROME DENGAN HIPOTIROIDISME

Authors

  • Innal Hamda Universitas Muslim Indonesia
  • Guntur Yohanes Universitas Muslim Indonesia
  • Aulia Wiratama Putra Universitas Muslim Indonesia
  • Muhammad Irfan Rahmatullah Universitas Muslim Indonesia
  • Nabilah Biyanti Universitas Muslim Indonesia

DOI:

https://doi.org/10.31004/jkt.v4i4.19217

Keywords:

Carpal Tunnel Syndrom, Hipotiroid, Hubungan

Abstract

Carpal Tunnel Syndrome (CTS) adalah sindrom neurokompresi saraf perifer yang paling umum. Penyebab umum CTS adalah kondisi seperti hipotiroidisme, kehamilan, menopause, obesitas, diabetes, dan lain-lain. Hubungan antara CTS dan hipotiroidisme bervariasi, berkisar antara 7 hingga 92 persen. Beberapa penelitian juga melaporkan tingginya prevalensi CTS pada pasien hipotiroid.  Penting untuk melakukan penelitian yang menggambarkan hubungan antara CTS dan hipotiroidisme, karena diagnosis dini diperlukan untuk menangani kedua kondisi tersebut. Penulis mencari, menyeleksi, dan memilih jurnal yang berkaitan dengan hubungan CTS dengan hipotiroid melalui beberapa database penelitian antara lain ScienceDirect, Google Scholar, PubMed, dan Wiley. Penelusuran penelitian dilakukan dengan menggunakan kata kunci “carpal tunnel syndrome” dan “hipotiroidisme”. Hasil dari pencarian literatur sejumlah 1.499 jurnal dengan 25 jurnal memenuhi kriteria seleksi melalui judul dan abstrak, dan 10 penelitian yang akan dianalisis lebih lanjut. Berbagai studi menunjukkan bahwa kejadian CTS berhubungan dengan hipotiroidisme. CTS pada pasien hipotiroid terjadi karena deposit musin atau mukopolisakarida pada saraf median.  Skrining tiroid disarankan menjadi pemeriksaan rutin bagi pasien CTS sebagai diagnosis dini dan memperbaiki prognosis pasien. CTS dapat diatasi pada pasien hipotiroid dengan menggunakan terapi penggantian hormon. Kejadian CTS berhubungan erat dengan kondisi hipotiroidisme.

References

Abd El-Monem Ali, H. (2023). Subclinical Peripheral Nerve Affection In Cases Of Subclinical Hypothyroidism. Al-Azhar Medical Journal, 52(2), 777–789. https://doi.org/10.21608/amj.2023.303752

Aboonq, M. S. (2015). Pathophysiology of carpal tunnel syndrome. Neurosciences, 20(1), 4–9.

Akarsu, E. O., Acar, H., Ozer, F., Günayd?n, S., Akarsu, Ö., Özcan, T. A., Özben, S., Mutlu, A., Bedir, M., Gül, G. Ç., Çokar, Ö., & Aktu?lu, M. B. (2013). Electromyograph?c F?ndings In Overt Hypothyroidism and Subclinical Hypothyroidism. Türk Nöroloji Dergisi, 19(4), 128–133. https://doi.org/10.4274/Tnd.05658

Aldaghri, F., Algahtani, M. S., Almutairi, T. A., Albusair, M., Bin Ghali, K., & Al Asim, F. S. (2020). Prevalence of Hypothyroidism Among Carpal Tunnel Syndrome Patients at a Hospital in Saudi Arabia. Cureus. https://doi.org/10.7759/cureus.12264

Annisa, D., Budhi Rianawati, S., Rahayu, M., Raisa, N., & Nandar Kurniawan, S. (2021). Carpal Tunnel Syndrome (Diagnosis And Management). JPHV (Journal of Pain, Vertigo and Headache), 2(1), 5–7. https://doi.org/10.21776/ub.jphv.2021.002.01.2

Dec, P., & Zyluk, A. (2018). Bilateral carpal tunnel syndrome – A review. Neurologia i Neurochirurgia Polska, 52(1), 79–83. https://doi.org/10.1016/j.pjnns.2017.09.009

Elnady, B., Rageh, E. M., Ekhouly, T., Fathy, S. M., Alshaar, M., Fouda, E. S., Attar, M., Abdelaal, A. M., El Tantawi, A., Algethami, M. M., & Bong, D. (2019). Diagnostic potential of ultrasound in carpal tunnel syndrome with different etiologies: Correlation of sonographic median nerve measures with electrodiagnostic severity. BMC Musculoskeletal Disorders, 20(1), 634. https://doi.org/10.1186/s12891-019-3010-5

Fernández-de-las-peñas, C., Arias-Buría, J. L., Ortega-Santiago, R., & De-la-Llave-Rincón, A. I. (2020). Understanding central sensitization for advances in management of carpal tunnel syndrome. F1000Research, 9, 605. https://doi.org/10.12688/f1000research.22570.1

Hidayati, H. B., Subadi, I., Fidiana, F., & Puspamaniar, V. A. (2022). Current diagnosis and management of carpal tunnel syndrome: A review. Anaesthesia, Pain & Intensive Care, 26(3), 394–404. https://doi.org/10.35975/apic.v26i3.1902

Joshi, A., Patel, K., Mohamed, A., Oak, S., Zhang, M. H., Hsiung, H., Zhang, A., & Patel, U. K. (2022). Carpal Tunnel Syndrome: Pathophysiology and Comprehensive Guidelines for Clinical Evaluation and Treatment. Cureus. https://doi.org/10.7759/cureus.27053

Karne, S. S. (2016). Carpal Tunnel Syndrome in Hypothyroidism. Journal Of Clinical And Diagnostic Research. https://doi.org/10.7860/JCDR/2016/16464.7316

Kasem, A. A. (2014). Carpal Tunnel Syndrome in Hypothyroid Patients: The Effect of Hormone Replacement Therapy. American Journal of Internal Medicine, 2(3), 54. https://doi.org/10.11648/j.ajim.20140203.14

Leng, O., & Razvi, S. (2019). Hypothyroidism in the older population. Thyroid Research, 12(1), 2. https://doi.org/10.1186/s13044-019-0063-3

Malakootian, M., Soveizi, M., Gholipour, A., & Oveisee, M. (2023). Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review. Cellular and Molecular Neurobiology, 43(5), 1817–1831. https://doi.org/10.1007/s10571-022-01297-2

Oktayoglu, P., Nas, K., Kilinç, F., Tasdemir, N., Bozkurt, M., & Yildiz, I. (2015). Assessment of the Presence of Carpal Tunnel Syndrome in Patients with Diabetes Mellitus, Hypothyroidism and Acromegaly. Journal of Clinical and Diagnostic Research?: JCDR, 9(6), OC14–OC18. https://doi.org/10.7860/JCDR/2015/13149.6101

Ortega-Santiago, R., de-la-Llave-Rincon, A. I., Laguarta-Val, S., Martinez-Perez, A., Pareja, J. A., & Fernandez-de-Las-Penas, C. (2012). Neurophysiological advances in carpal tunnel syndrome: Process of central sensitisation or local neuropathy. Revista De Neurologia, 54(8), 490–496.

Osiak, K., Elnazir, P., Walocha, J. A., & Pasternak, A. (2022). Carpal tunnel syndrome: State-of-the-art review. Folia Morphologica, 81(4), 851–862. https://doi.org/10.5603/FM.a2021.0121

Peeters, R. P. (2017). Subclinical Hypothyroidism. New England Journal of Medicine, 376(26), 2556–2565. https://doi.org/10.1056/NEJMcp1611144

Roshanzamir, S., Azarang, A., & Dabbaghmanesh, A. (2016). Rational For Hypothyroidism Screening In Carpal Tunnel Syndrome Patients Without Definite Predisposing Factor. Journal of Musculoskeletal Research, 19(04), 1650020. https://doi.org/10.1142/S0218957716500202

Tang, N., Ma, J., Tao, R., Chen, Z., Yang, Y., He, Q., Lv, Y., Lan, Z., & Zhou, J. (2022). The effects of the interaction between BMI and dyslipidemia on hypertension in adults. Scientific Reports, 12(1), 927. https://doi.org/10.1038/s41598-022-04968-8

Tonga, F., & Bahadir, S. (2021). The factors associated with carpal tunnel syndrome severity. Turkish Neurosurgery. https://doi.org/10.5137/1019-5149.JTN.34519-21.2

Vashishtha, M., Varghese, B., Mosley, F., Kadakia, A., & De Jager, W. (2016). Screening for thyroid dysfunction and diabetes in patients with carpal tunnel syndrome. The Surgeon, 14(3), 147–149. https://doi.org/10.1016/j.surge.2014.11.003

Wielemborek, P., Kapica-Topczewska, K., Pogorzelski, R., Bartoszuk, A., Kochanowicz, J., & Ku?akowska, A. (2022). Carpal tunnel syndrome conservative treatment: A literature review. Post?py Psychiatrii i Neurologii, 31(2), 85–94. https://doi.org/10.5114/ppn.2022.116880

Wipperman, J., & Goerl, K. (2016). Carpal Tunnel Syndrome: Diagnosis and Management. American Family Physician, 94(12), 993–999.

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Published

2023-12-29